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经验公式（希尔记法）:
C30H57NO12
化学文摘社编号:
分子量:
623.77
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
Lactosyl(β) Sphingosine (d18:1), Avanti Research™ - A Croda Brand 860542P, powder
SMILES string
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@](N)([H])CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O[C@H](O2)[C@H](O)[C@@H](O)[C@H]([C@H]2CO)O
InChI
1S/C30H57NO12/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20(34)19(31)18-40-29-27(39)25(37)28(22(17-33)42-29)43-30-26(38)24(36)23(35)21(16-32)41-30/h14-15,19-30,32-39H,2-13,16-18,31H2,1H3/b15-14+/t19-,20+,21+,22+,23-,24-,25+,26+,27+,28+,29+,30-/m0/s1
InChI key
MQKSCOKUMZMISB-GPWKTZPCSA-N
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (860542P-5mg)
pkg of 1 × 50 mg (860542P-50mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860542P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
Application
Lactosyl(β) Sphingosine (d18:1) or D-lactosyl-β1-1′-D-erythro-sphingosine has been used as an internal standard for the quantification of psychosine using tandem mass spectrometry. It may be used to screen lipids that rapidly and reversibly alter transepithelial electrical resistance (TER) or tight junction (TJ) permeability in epithelial tissue. It may also be used as a standard to determine the extent of recovery of lyso-neutral glycosphingolipids (lyso-n-GSLs) from the Sephadex column.
Biochem/physiol Actions
Lactosyl sphingosine exhibits better hemolytic activity than lysolecithin.
General description
Lactosyl sphingosine is a glycosylsphingosine (Lyso-GSL), which is found in bovine brain white matter extract.
Packaging
5 mL Amber Glass Screw Cap Vial (860542P-50mg)
5 mL Amber Glass Screw Cap Vial (860542P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
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Journal of lipid research, 44(7), 1413-1419 (2003-05-06)
We describe a new method that permits quantification in the pmol to nmol range of three lyso-neutral glycosphingolipids (lyso-n-GSLs), glucosylsphingosine (GlcSph), galactosylsphingosine (GalSph), and lactosylsphingosine, in the same sample as neutral glycosphingolipids (n-GSLs). Lyso-n-GSLs and n-GSLs are initially obtained from
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