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关于此项目
经验公式（希尔记法）:
C38H71NO13
化学文摘社编号:
分子量:
749.97
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
C8 L-threo-Lactosyl(β) Ceramide (d18:1/8:0), Avanti Research™ - A Croda Brand 860575P, powder
InChI key
JUCWRRXMPGRQOG-CKTHHAJGSA-N
SMILES string
CCCCCCCCCCCCC/C=C/[C@@](O)([H])[C@@]([H])(NC(CCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O[C@H](O2)[C@H](O)[C@@H](O)[C@H]([C@H]2CO)O
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (860575P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860575P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
General description
C8 L-threo-Lactosyl(β) Ceramide (d18:1/8:0) is a synthetic glycosphingolipid (GSL) with nonnatural stereochemistry.
Application
C8 L-threo-Lactosyl(β) Ceramide (d18:1/8:0) may be used to disrupt brain-derived neurotropic factor (BDNF)-induced integrin clustering.
Biochem/physiol Actions
C8 L-threo-Lactosyl(β) Ceramide (d18:1/8:0) is a caveolar uptake inhibitor, which blocks SV40 virus infection. It also prevents E1-integrin activation and downstream signaling. C8 L-threo-Lactosyl(β) Ceramide (d18:1/8:0) can deter the aggregation of lipids and proteins into glycosphingolipids (GSLs) and cholesterol-enriched microdomains (rafts) at the plasma membrane (PM).
Packaging
5 mL Amber Glass Screw Cap Vial (860575P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
法规信息
涉药品监管产品
此项目有
Bidirectional remodeling of beta1-integrin adhesions during chemotropic regulation of nerve growth
Carlstrom LP, et al.
BMC biology, 9(1), 82-82 (2011)
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