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Merck
CN

870262P

Avanti

18:1 Dodecanyl PE

Avanti Research - A Croda Brand

别名:

Sodium (2R)-2,3-bis{[(9Z)-octadec-9-enoyl]oxy}propyl 2-[(11-carboxyundecanoyl)amino]ethyl phosphate

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关于此项目

经验公式(希尔记法):
C53H97NO11PNa
化学文摘社编号:
分子量:
978.30
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

18:1 Dodecanyl PE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(dodecanyl) (sodium salt), powder

SMILES string

[H][C@@](COP([O-])(OCCN([H])C(CCCCCCCCCCC(O)=O)=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

InChI

1S/C53H98NO11P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-31-35-39-43-52(58)62-47-49(65-53(59)44-40-36-32-26-24-22-20-18-16-14-12-10-8-6-4-2)48-64-66(60,61)63-46-45-54-50(55)41-37-33-29-27-28-30-34-38-42-51(56)57;/h17-20,49H,3-16,21-48H2,1-2H3,(H,54,55)(H,56,57)(H,60,61);/q;+1/p-1/b19-17-,20-18-;/t49-;/m1./s1

InChI key

AHHCDNFLXOEQMC-VXILFBGRSA-M

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (870262P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 870262P

shipped in

dry ice

storage temp.

−20°C

Application

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-dodecanoyl (18:1 Dodecanyl PE) may be used in preparation of fusogenic and unilamellar liposomes.

General description

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(dodecanoyl) (18:1 Dodecanyl PE) or N-dod-PE, is a fusogenic lipid, belonging to the class of head group modified functionalized lipids.

Packaging

5 mL Clear Glass Sealed Ampule (870262P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

wgk

WGK 3

法规信息

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T Shangguan et al.
Gene therapy, 7(9), 769-783 (2000-05-24)
A unique method for formulation of plasmid DNA with phospholipids has been devised for the purpose of producing vehicles that can mediate gene delivery and transfection of living cells. The polycation, spermine, was used to condense plasmid DNA within a
Rico C Gunawan et al.
Biomaterials, 31(5), 900-907 (2009-11-03)
Targeted drug delivery to inflamed or injured vascular endothelial cells (ECs) and smooth muscle cells (SMCs) may provide a precise and effective therapeutic treatment for cardiovascular diseases. Upregulation of cytokine-regulated cell surface receptors, intercellular cell adhesion molecule-1 (ICAM) and endothelial-leukocyte

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