产品名称
C20:4花生四烯乙醇胺磷酸酯, Avanti Research™ - A Croda Brand 870440C
shipped in
dry ice
storage temp.
−20°C
SMILES string
O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)NCCOP(O)([O-])=O.[Na+]
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (870440C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 870440C
concentration
1 mg/mL (870440C-1mg)
General description
Anandamide (AEA) is an endogenous ligand for cannabinoid receptors. It is an N-acyl ethanolamide derivative of C20,4 fatty acid. AEA is a lipid neurotransmitter. It is synthesized and released by the neurons in the brain and macrophages. AEA is a lipophilic and poorly water-soluble compound. Anandamide phosphate (pAEA) is dephosphorylated by phosphatase to yield anandamide.{56)
Biochem/physiol Actions
Anandamide (AEA) is involved in many physiological and pathophysiological functions, such as regulation of energy consumption and balance. It also plays an important role in initiation and control of inflammation and modulatory effects on sensory and autonomic nerve signaling.
Packaging
5 mL Amber Screw Cap Bottle with Foil Bag Argon Overseal (870440C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
新产品
此项目有
Multiple pathways involved in the biosynthesis of anandamide
Liu J, et al.
Neuropharmacology, 54(1), 1-7 (2008)
Anandamide prodrugs: 1. Water-soluble phosphate esters of arachidonylethanolamide and R-methanandamide
Juntunen J, et al.
European Journal of Pharmaceutical Sciences, 19(1), 37-43 (2003)
Anandamide and its metabolites: what are their roles in the kidney?
Ritter J K, et al.
Frontiers in Bioscience, 8(2-3), 264-264 (2016)
Targeting fatty-acid amide hydrolase with prodrugs for CNS-selective therapy
Meinig J M, et al.
ACS Chemical Neuroscience, 8(11), 2468-2476 (2017)
Anandamide receptors
Di Marzo V, et al.
Prostaglandins, Leukotrienes, and Essential Fatty Acids, 66(2-3), 377-391 (2002)
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