产品名称
C20:4花生四烯乙醇胺磷酸酯, Avanti Research™ - A Croda Brand 870440C
方案
>99% (TLC)
表单
liquid
包装
pkg of 1 × 1 mL (870440C-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 870440C
浓度
1 mg/mL (870440C-1mg)
运输
dry ice
储存温度
−20°C
SMILES字符串
O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)NCCOP(O)([O-])=O.[Na+]
一般描述
Anandamide (AEA) is an endogenous ligand for cannabinoid receptors. It is an N-acyl ethanolamide derivative of C20,4 fatty acid. AEA is a lipid neurotransmitter. It is synthesized and released by the neurons in the brain and macrophages. AEA is a lipophilic and poorly water-soluble compound. Anandamide phosphate (pAEA) is dephosphorylated by phosphatase to yield anandamide.{56)
生化/生理作用
Anandamide (AEA) is involved in many physiological and pathophysiological functions, such as regulation of energy consumption and balance. It also plays an important role in initiation and control of inflammation and modulatory effects on sensory and autonomic nerve signaling.
包装
5 mL Amber Screw Cap Bottle with Foil Bag Argon Overseal (870440C-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system
储存分类代码
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
闪点(°F)
does not flash
闪点(°C)
does not flash
法规信息
新产品
此项目有
Anandamide prodrugs: 1. Water-soluble phosphate esters of arachidonylethanolamide and R-methanandamide
Juntunen J, et al.
European Journal of Pharmaceutical Sciences, 19(1), 37-43 (2003)
Anandamide and its metabolites: what are their roles in the kidney?
Ritter J K, et al.
Frontiers in Bioscience, 8(2-3), 264-264 (2016)
Multiple pathways involved in the biosynthesis of anandamide
Liu J, et al.
Neuropharmacology, 54(1), 1-7 (2008)
Targeting fatty-acid amide hydrolase with prodrugs for CNS-selective therapy
Meinig J M, et al.
ACS Chemical Neuroscience, 8(11), 2468-2476 (2017)
Anandamide receptors
Di Marzo V, et al.
Prostaglandins, Leukotrienes, and Essential Fatty Acids, 66(2-3), 377-391 (2002)
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