产品名称
oxPAPC, Avanti Research™ - A Croda Brand 870604P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 500 μg (870604P-500ug)
manufacturer/tradename
Avanti Research™ - A Croda Brand 870604P
lipid type
phosphoglycerides
phospholipids
shipped in
dry ice
storage temp.
−20°C
General description
氧化1-棕榈酰基-2-花生四烯酰基-sn-甘油-3-磷酸胆碱（OxPAPC）是氧化磷脂和氧化低密度脂蛋白（LDL）生物活性成分的混合物。
Application
氧化1-棕榈酰-2-花生四烯醇-sn-甘油-3-磷酸胆碱（OxPAPC）适用于体外刺激鼠肺泡巨噬细胞。它也适用于研究其对人主动脉内皮细胞代谢重编程的作用。
Biochem/physiol Actions
氧化1-棕榈酰-2-花生四烯醇-sn-甘油-3-磷酸胆碱（OxPAPC）对人肺内皮单层细胞具有屏障保护作用。该脂质通过刺激促炎和抗炎途径诱导内皮功能障碍。OxPAPC在动脉粥样硬化病变和其他慢性炎症部位中高度积累。
Packaging
5 mL透明玻璃密封安瓿（870604P-500ug）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
Arid5a-deficient mice are highly resistant to bleomycin-induced lung injury
Dubey PK, et al.
International Immunology, 29(2), 79-85 (2017)
Identification of prostaglandin E2 receptor subtype 2 as a receptor activated by OxPAPC
Li R, et al.
Circulation Research, 98(5), 642-650 (2006)
Signal transduction pathways activated in human pulmonary endothelial cells by OxPAPC, a bioactive component of oxidized lipoproteins
Birukov KG, et al.
Microvascular Research, 67(1), 18-28 (2004)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 870604P-500UG | 04061835353804 |