产品名称
C16-02:0 DG, Avanti Research™ - A Croda Brand 878118P, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 5 mg (with screw cap (878118P-5mg))
制造商/商品名称
Avanti Research™ - A Croda Brand 878118P
运输
dry ice
储存温度
−20°C
SMILES字符串
OC[C@]([H])(OC(C)=O)COCCCCCCCCCCCCCCCC
一般描述
C16-02:0 DG, also called as 1-O-hexadecyl-2-acetyl-sn-glycerol (HAG), is an alkylacylglycerol and a bioactive lipid. Structurally, HAG contains primary alcohol group at the C3 position.
应用
C16-02:0 DG or 1-O-hexadecyl-2-acetyl-sn-glycerol (HAG) may be used to prevent 1-O-acyl-NAS formation.
生化/生理作用
C16-02:0 DG or 1-O-hexadecyl-2-acetyl-sn-glycerol (HAG) is a diacylglycerol (DAG) antagonist with a potential to inhibit protein kinase C (PKC) activity. It also has an ability to inhibit growth of human promyelocytic leukemia cell line HL-60. HAG serves as a precursor in the biosynthesis of platelet-activating factor.
包装
5 mL PTFE Vial with Screw Cap (878118P-5mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
Jin Tao et al.
Cellular signalling, 21(9), 1436-1443 (2009-05-15)
Corticotropin-releasing factor (CRF) receptors have been demonstrated to be widely expressed in the central nervous system and in many peripheral tissues of mammalians. However, it is still unknown whether CRF receptors will function in cerebellar Purkinje neurons. In the present
M J McNamara et al.
Biochemical and biophysical research communications, 122(2), 824-830 (1984-07-31)
The human promyelocytic leukemia cell line HL-60 can be differentiated to cells resembling either neutrophils or mononuclear phagocytes by a diverse group of stimuli. However, the underlying mechanisms remain unknown. We report that 1-0-hexadecyl-2-acetyl-sn-glycerol inhibits the growth of HL-60 cells
Akira Abe et al.
Journal of lipid research, 48(10), 2255-2263 (2007-07-14)
A novel lysosomal phospholipase A(2) (LPLA2) with specificity toward phosphatidylethanolamine and phosphatidylcholine was previously purified and cloned. LPLA2 transfers sn-1 or sn-2 acyl groups of phospholipids to the C1 hydroxyl of the short-chain ceramide N-acetylsphingosine (NAS) under acidic conditions. The
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