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Merck
CN

880430C

Avanti

18:1 PEG350 PE

Avanti Research™ - A Croda Brand

别名:

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] (ammonium salt)

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关于此项目

化学文摘社编号:
474922-90-2
UNSPSC代码:
51171641
NACRES:
NA.25

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产品名称

18:1 PEG350 PE, Avanti Research™ - A Croda Brand 880430C

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 2.5 mL (880430C-25mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 880430C

浓度

10 mg/mL (880430C-25mg)

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

应用

18:1 PEG350 PE is suitable for liposome preparation.

生化/生理作用

Polyethylene glycol (PEG)-lipid conjugates are used extensively to improve circulation times for liposome encapsulated drugs. It promotes sustained injectable delivery system for insulin and superoxide dismutase. Cationic liposomes incorporating PEG-lipid is useful as carriers for oligonucleotides resulting in enhanced uptake by cells.

包装

5 mL Clear Glass Sealed Ampule (880430C-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system, Liver,Kidney

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Pharmacodynamics of insulin in polyethylene glycol-coated liposomes
Kim A, et al.
International Journal of Pharmaceutics, 180(1), 75-81 (1999)
Intravenous administration of superoxide dismutase entrapped in long circulating liposomes: II. In vivo fate in a rat model of adjuvant arthritis
Corvo M, et al.
Biochimica et Biophysica Acta - Biomembranes, 1419(2), 325-334 (1999)
A protocol for the systematic and quantitative measurement of protein?lipid interactions using the liposome-microarray-based assay.
Saliba AE, et al.
Nature Protocols, 11(6), 15621-15627 (2016)
Cationic liposomes coated with polyethylene glycol as carriers for oligonucleotides
Meyer O, et al.
The Journal of biological chemistry, 273(25), 15621-15627 (1998)
Selective transfer of a lipophilic prodrug of 5-fluorodeoxyuridine from immunoliposomes to colon cancer cells
Koning GA, et al.
Biochimica et Biophysica Acta - Biomembranes, 1420(1-2), 153-167 (1999)

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