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Merck
CN

880500P

Avanti

16:0 PEG550 PE

Avanti Research - A Croda Brand

别名:

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] (ammonium salt)

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化学文摘社编号:
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

16:0 PEG550 PE, Avanti Research - A Croda Brand 880500P, powder

InChI

1S/C63H124NO22P.H3N/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-61(65)83-58-60(86-62(66)31-29-27-25-23-21-19-17-15-13-11-9-7-5-2)59-85-87(68,69)84-33-32-64-63(67)82-57-56-81-55-54-80-53-52-79-51-50-78-49-48-77-47-46-76-45-44-75-43-42-74-41-40-73-39-38-72-37

InChI key

VJMCGROHAQCSGJ-CSZVLRKSSA-N

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (880500P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 880500P

shipped in

dry ice

storage temp.

−20°C

Biochem/physiol Actions

Polyethylene glycol (PEG) conjugated phospholipids are known to protect the steric nature of liposomes. Hence, they are commonly recommended for use in liposome formulation. PEGylated lipids are used as drug carriers. Use of highly concentrated PEG-lipids makes the possibility of mixed micelles.

General description

16:0 PEG550 PE is a polyethylene glycol (PEG) conjugated phospholipid. The molecular weight and exact mass are averages based on the polydispersity of PEG.

Packaging

5 mL Clear Glass Sealed Ampule (880500P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids

wgk

WGK 3


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Sirkku Hanski et al.
Biomacromolecules, 11(12), 3440-3447 (2010-10-27)
We report on highly ordered oblique self-assemblies in ionic complexes of PEGylated triple-tail lipids and cationic polypeptides, as directed by side-chain crystallization, demonstrating also reversible oblique-to-hexagonal order-order transitions upon melting of the side chains. This is achieved in bulk by
G F Peacock et al.
Drug delivery, 10(1), 29-34 (2003-01-30)
A new cholesterol-carborane conjugate (BCH) has been synthesized as a potential targeting agent for boron neutron capture therapy (BNCT) of cancers. The compound is extremely water insoluble and was formulated in two liposomal formulations to determine if the compound could
Maria C Sandström et al.
Langmuir : the ACS journal of surfaces and colloids, 23(8), 4192-4198 (2007-03-09)
Polyethylene glycol (PEG)-conjugated lipids are commonly employed for steric stabilization of liposomes. When added in high concentrations PEG-lipids induce formation of mixed micelles, and depending on the lipid composition of the sample, these may adapt either a discoidal or a
Brian J Nablo et al.
Biophysical journal, 95(3), 1157-1164 (2008-07-23)
Nonelectrolyte polymers of poly(ethylene glycol) (PEG) were used to estimate the diameter of the ion channel formed by the Bacillus anthracis protective antigen 63 (PA(63)). Based on the ability of different molecular weight PEGs to partition into the pore and

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