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Merck
CN

880710C

Avanti

14:0 PEG1000 PE

Avanti Research - A Croda Brand

别名:

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] (ammonium salt)

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化学文摘社编号:
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

14:0 PEG1000 PE, Avanti Research - A Croda Brand 880710C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[NH4+]

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (880710C-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 880710C

concentration

10 mg/mL (880710C-25mg)

shipped in

dry ice

storage temp.

−20°C

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Application

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] (14:0 PEG1000 PE) is suitable for use in lipid aggregates to characterize and study its use as a coating and a carrier in capillary electrophoresis. It might be used to prepare sterically stabilized liposome and study its characteristics by small-angle X-ray scattering (SAXS) method.

Biochem/physiol Actions

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] (14:0 PEG1000 PE) is useful in preparing polyethylene glycol (PEG)-stabilized lipid aggregates, which serve as model membranes in biotechnical and pharmaceutical applications. PEG conjugated lipids improve liposome packing in the water/hydrocarbon interface. PEGs of molecular mass less than or equal to 5000 is preferred for vesicle coating serving for efficient delivery of the drug.

Packaging

5 mL Clear Glass Sealed Ampule (880710C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

法规信息

危险化学品
易制毒化学品(2类)
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Maria V Lindén et al.
Electrophoresis, 29(4), 852-862 (2008-01-24)
PEG-stabilized lipid aggregates are a promising new class of model membranes in biotechnical and pharmaceutical applications. CE techniques, field-flow fractionation, light scattering, quartz crystal microbalance (QCM), and microscopic techniques were used to study aggregates composed of 1-palmitoyl-2-oleyl-sn-glycero-phosphatidylcholine (POPC) and PEG-lipid
Z Varga et al.
Chemistry and physics of lipids, 165(4), 387-392 (2012-01-10)
Synchrotron small-angle X-ray scattering analysis of the bilayer structure of a pharmacologically relevant sterically stabilized liposome system is presented. Describing the electron density profile of the bilayer with the superposition of Gaussian functions, the contribution of the poly(ethylene glycol) (PEG)

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