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关于此项目
经验公式（希尔记法）:
C34H68NO4Cl
化学文摘社编号:
分子量:
590.36
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
14:0 TAP, Avanti Research™ - A Croda Brand 890860C
InChI key
WOSYUIOSAOFINL-UHFFFAOYSA-M
SMILES string
[H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[Cl-]
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 2.5 mL (890860C-25mg)
pkg of 2 × 4 mL (890860C-200mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 890860C
concentration
10 mg/mL (890860C-25mg)
25 mg/mL (890860C-200mg)
lipid type
cationic lipids
transfection
shipped in
dry ice
storage temp.
−20°C
Application
1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is suitable for:
- preparation of cationic liposomes
- reconstitution of bacteriorhodopsin (BR) and proteorhodopsin (PR) into liposomes
- composing lipid–styrene maleic acid (SMA) complexes
- liposome preparation by double emulsion method
Biochem/physiol Actions
1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is useful for bicelle formation. Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.
General description
1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is a saturated cationic lipid with a positively charged headgroup. It has an alkyl chain length with 14 carbon atoms.
Packaging
5 mL Clear Glass Sealed Ampule (890860C-200mg)
5 mL Clear Glass Sealed Ampule (890860C-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
target_organs
Liver,Kidney, Respiratory system
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
易制毒化学品（2类）
危险化学品
此项目有
Reverse osmosis membranes based on a supported lipid bilayer with gramicidin A water channels
Saeki D, et al.
Desalination, 375, 48-53 (2015)
Lipid-induced dynamics of photoreceptors monitored by time-resolved step-scan FTIR spectroscopy
Jawurek M, et al.
Chemical Physics, 512, 53-61 (2018)
Masafumi Tanaka et al.
Biochimica et biophysica acta. Biomembranes, 1862(5), 183209-183209 (2020-02-01)
Styrene maleic acid copolymers (SMA) form discoidal lipid nanoparticles (lipid nanodisks) that mimic plasma high-density lipoproteins. We have previously prepared and characterized lipid nanodisks composed of SMA and the neutral phospholipid 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). In the present study, we tested whether
A E Regelin et al.
Biochimica et biophysica acta, 1464(1), 151-164 (2000-03-08)
In order to investigate the relationship between lipid structure and liposome-mediated gene transfer, we have studied biophysical parameters and transfection properties of monocationic DOTAP analogs, systematically modified in their non-polar hydrocarbon chains. Stability, size and (by means of anisotropy profiles)
Nishu Kanwa et al.
Physical chemistry chemical physics : PCCP, 22(6), 3234-3244 (2020-01-30)
In the present contribution, we investigate the interactions of lipid bilayer membranes of different charges and different phase states with aliphatic amino acids of varying charge (aspartic acid, glutamic acid, arginine and lysine) and hydrophobicity (serine, leucine and valine) by
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