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Merck
CN

890860C

Avanti

14:0 TAP

Avanti Research™ - A Croda Brand

别名:

1,2-dimyristoyl-3-trimethylammonium-propane (chloride salt)

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关于此项目

经验公式（希尔记法）:
C34H68NO4Cl
化学文摘社编号:
197974-74-6
分子量:
590.36
MDL编号:
MFCD16294915
UNSPSC代码:
12352211
NACRES:
NA.25

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产品名称

14:0 TAP, Avanti Research™ - A Croda Brand 890860C

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 2.5 mL (890860C-25mg)
pkg of 2 × 4 mL (890860C-200mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 890860C

浓度

10 mg/mL (890860C-25mg)
25 mg/mL (890860C-200mg)

脂质类型

cationic lipids
transfection

运输

dry ice

储存温度

−20°C

SMILES字符串

[H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[Cl-]

InChI key

WOSYUIOSAOFINL-UHFFFAOYSA-M

相关类别

一般描述

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is a saturated cationic lipid with a positively charged headgroup. It has an alkyl chain length with 14 carbon atoms.

应用

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is suitable for:
  • preparation of cationic liposomes
  • reconstitution of bacteriorhodopsin (BR) and proteorhodopsin (PR) into liposomes
  • composing lipid–styrene maleic acid (SMA) complexes
  • liposome preparation by double emulsion method

生化/生理作用

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is useful for bicelle formation. Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.

包装

5 mL Clear Glass Sealed Ampule (890860C-200mg)
5 mL Clear Glass Sealed Ampule (890860C-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

靶器官

Liver,Kidney, Respiratory system

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

易制毒化学品（2类）
危险化学品
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历史批次信息供参考:

分析证书(COA)

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Lipid-induced dynamics of photoreceptors monitored by time-resolved step-scan FTIR spectroscopy
Jawurek M, et al.
Chemical Physics, 512, 53-61 (2018)
Masafumi Tanaka et al.
Biochimica et biophysica acta. Biomembranes, 1862(5), 183209-183209 (2020-02-01)
Styrene maleic acid copolymers (SMA) form discoidal lipid nanoparticles (lipid nanodisks) that mimic plasma high-density lipoproteins. We have previously prepared and characterized lipid nanodisks composed of SMA and the neutral phospholipid 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). In the present study, we tested whether
Reverse osmosis membranes based on a supported lipid bilayer with gramicidin A water channels
Saeki D, et al.
Desalination, 375, 48-53 (2015)
A E Regelin et al.
Biochimica et biophysica acta, 1464(1), 151-164 (2000-03-08)
In order to investigate the relationship between lipid structure and liposome-mediated gene transfer, we have studied biophysical parameters and transfection properties of monocationic DOTAP analogs, systematically modified in their non-polar hydrocarbon chains. Stability, size and (by means of anisotropy profiles)
Nishu Kanwa et al.
Physical chemistry chemical physics : PCCP, 22(6), 3234-3244 (2020-01-30)
In the present contribution, we investigate the interactions of lipid bilayer membranes of different charges and different phase states with aliphatic amino acids of varying charge (aspartic acid, glutamic acid, arginine and lysine) and hydrophobicity (serine, leucine and valine) by
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