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Merck
CN

890860C

Avanti

14:0 TAP

Avanti Research - A Croda Brand

别名:

1,2-dimyristoyl-3-trimethylammonium-propane (chloride salt)

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关于此项目

经验公式(希尔记法):
C34H68NO4Cl
化学文摘社编号:
分子量:
590.36
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

14:0 TAP, Avanti Research - A Croda Brand 890860C

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (890860C-25mg), pkg of 2 × 4 mL (890860C-200mg)

manufacturer/tradename

Avanti Research - A Croda Brand 890860C

concentration

10 mg/mL (890860C-25mg), 25 mg/mL (890860C-200mg)

lipid type

cationic lipids
transfection

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[Cl-]

InChI key

WOSYUIOSAOFINL-UHFFFAOYSA-M

General description

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is a saturated cationic lipid with a positively charged headgroup. It has an alkyl chain length with 14 carbon atoms.

Application

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is suitable for:
  • preparation of cationic liposomes
  • reconstitution of bacteriorhodopsin (BR) and proteorhodopsin (PR) into liposomes
  • composing lipid–styrene maleic acid (SMA) complexes
  • liposome preparation by double emulsion method

Biochem/physiol Actions

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is useful for bicelle formation. Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.

Packaging

5 mL Clear Glass Sealed Ampule (890860C-200mg)
5 mL Clear Glass Sealed Ampule (890860C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

法规信息

易制毒化学品(2类)
危险化学品

此项目有



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Masafumi Tanaka et al.
Biochimica et biophysica acta. Biomembranes, 1862(5), 183209-183209 (2020-02-01)
Styrene maleic acid copolymers (SMA) form discoidal lipid nanoparticles (lipid nanodisks) that mimic plasma high-density lipoproteins. We have previously prepared and characterized lipid nanodisks composed of SMA and the neutral phospholipid 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). In the present study, we tested whether
Lipid-induced dynamics of photoreceptors monitored by time-resolved step-scan FTIR spectroscopy
Jawurek M, et al.
Chemical Physics, 512, 53-61 (2018)
Reverse osmosis membranes based on a supported lipid bilayer with gramicidin A water channels
Saeki D, et al.
Desalination, 375, 48-53 (2015)



全球贸易项目编号

货号GTIN
890860C-25MG04061837668920
890860C-200MG04061837668913