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经验公式（希尔记法）:
C34H68NO4Cl
化学文摘社编号:
分子量:
590.36
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
14:0 TAP, Avanti Research™ - A Croda Brand
InChI
1S/C34H68NO4.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-33(36)38-31-32(30-35(3,4)5)39-34(37)29-27-25-23-21-19-17-15-13-11-9-7-2;/h32H,6-31H2,1-5H3;1H/q+1;/p-1
InChI key
WOSYUIOSAOFINL-UHFFFAOYSA-M
SMILES string
[H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[Cl-]
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 200 mg (890860P-200mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
cationic lipids
transfection
shipped in
dry ice
storage temp.
−20°C
Application
1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is suitable for:
- the preparation of cationic liposomes
- reconstitution of bacteriorhodopsin (BR) and proteorhodopsin (PR) into liposomes
- composing lipid–styrene maleic acid (SMA) complexes
- liposome preparation by double emulsion method
Biochem/physiol Actions
1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is useful for bicelle formation. Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.
General description
1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is a saturated cationic lipid with a positively charged headgroup. It has an alkyl chain length with 14 carbon atoms.
Packaging
5 mL Amber Glass Screw Cap Vial (890860P-200mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
Reverse osmosis membranes based on a supported lipid bilayer with gramicidin A water channels
Saeki D, et al.
Desalination, 375, 48-53 (2015)
Lipid-induced dynamics of photoreceptors monitored by time-resolved step-scan FTIR spectroscopy
Jawurek M, et al.
Chemical Physics, 512, 53-61 (2018)
Masafumi Tanaka et al.
Biochimica et biophysica acta. Biomembranes, 1862(5), 183209-183209 (2020-02-01)
Styrene maleic acid copolymers (SMA) form discoidal lipid nanoparticles (lipid nanodisks) that mimic plasma high-density lipoproteins. We have previously prepared and characterized lipid nanodisks composed of SMA and the neutral phospholipid 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). In the present study, we tested whether
A E Regelin et al.
Biochimica et biophysica acta, 1464(1), 151-164 (2000-03-08)
In order to investigate the relationship between lipid structure and liposome-mediated gene transfer, we have studied biophysical parameters and transfection properties of monocationic DOTAP analogs, systematically modified in their non-polar hydrocarbon chains. Stability, size and (by means of anisotropy profiles)
Nishu Kanwa et al.
Physical chemistry chemical physics : PCCP, 22(6), 3234-3244 (2020-01-30)
In the present contribution, we investigate the interactions of lipid bilayer membranes of different charges and different phase states with aliphatic amino acids of varying charge (aspartic acid, glutamic acid, arginine and lysine) and hydrophobicity (serine, leucine and valine) by
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