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Merck
CN

890870C

Avanti

16:0 TAP

Avanti Research - A Croda Brand

别名:

1,2-dipalmitoyl-3-trimethylammonium-propane (chloride salt)

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关于此项目

经验公式(希尔记法):
C38H76NO4Cl
化学文摘社编号:
分子量:
646.47
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

16:0 TAP, Avanti Research - A Croda Brand 890870C

InChI

1S/C38H76NO4.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-37(40)42-35-36(34-39(3,4)5)43-38(41)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;/h36H,6-35H2,1-5H3;1H/q+1;/p-1

InChI key

KYARZEFZZOGPGS-UHFFFAOYSA-M

SMILES string

[H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Cl-]

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (890870C-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 890870C

concentration

10 mg/mL (890870C-25mg)

lipid type

cationic lipids
transfection

shipped in

dry ice

storage temp.

−20°C

Application

1,2-dipalmitoyl-3-trimethylammonium-propane (16:0 TAP) is suitable to prepare lipid monolayer/liposome:
  • to mimic the presence of the cationic charge localized in the membrane for understanding the electrostatic effects in the biological membranes and to study its interaction with zearalenone and selenate ions
  • to study its effect on the L-pro catalyzed reaction
  • to serve as a positive control, to determine the effectiveness of anionic phospholipids for pro-inflammatory responses

Biochem/physiol Actions

1,2-dipalmitoyl-3-trimethylammonium-propane (16:0 TAP) liposomes are known to promote elevated pro-inflammatory responses.

General description

1,2-dipalmitoyl-3-trimethylammonium-propane (16:0 TAP) is a cationic lipid and a diol based transfection reagent.

Packaging

5 mL Clear Glass Sealed Ampule (890870C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

法规信息

危险化学品
易制毒化学品(2类)
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Naomi Benne et al.
Journal of controlled release : official journal of the Controlled Release Society, 291, 135-146 (2018-10-27)
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Hirose M, et al.
Journal of Chemistry, 2019 (2019)
Barbara Gzyl-Malcher et al.
The Journal of membrane biology, 250(3), 273-284 (2017-04-30)
The impact of zearalenone and selenate ions on the monolayers of 1,2-dipalmitoyl-phosphatidylcholine (DPPC), 1,2-dipalmitoyl-3-trimethylammonium-propane (DPTAP), and the lipid mixtures (phospholipids and galactolipids) extracted from wheat plasmalemma has been studied using Langmuir trough technique and Brewster angle microscopy (BAM). The zearalenone
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International journal of nanomedicine, 14, 8923-8941 (2019-12-10)
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Chemosphere, 247, 125876-125876 (2020-01-25)
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