产品名称
17(S)-HDHA, Avanti Research™ - A Croda Brand 900125E, ethanol solution
方案
>99% (TLC)
表单
ethanol solution
包装
pkg of 1 × 1 mL (900125E-100ug)
pkg of 1 × 1 mL (900125E-500ug)
制造商/商品名称
Avanti Research™ - A Croda Brand 900125E
浓度
0.1 mg/mL (900125E-100ug)
0.5 mg/mL (900125E-500ug)
脂质类型
neutral lipids
neutral glycerides
运输
dry ice
储存温度
−70°C
SMILES字符串
CC/C=C\C[C@H](O)/C=C/C=C\C/C=C\C/C=C\C/C=C\CCC(O)=O
InChI
1S/C22H32O3/c1-2-3-15-18-21(23)19-16-13-11-9-7-5-4-6-8-10-12-14-17-20-22(24)25/h3,5-8,11-16,19,21,23H,2,4,9-10,17-18,20H2,1H3,(H,24,25)/b7-5-,8-6-,13-11-,14-12-,15-3-,19-16+/t21-/m0/s1
InChI key
SWTYBBUBEPPYCX-YTQNUIGOSA-N
一般描述
Docosahexaenoic acid (DHA) is an omega-3 polyunsaturated fatty acid (PUFA) with 22 carbons and six double bonds. The first double bond occurring at position three from the methyl terminus (22:6 n-3). DHA is a component of phospholipid membranes and the myelin sheath. It is the most abundant PUFA found in the brain and localized predominantly to the gray matter.
生化/生理作用
Docosahexaenoic acid (DHA) exhibits various physiological processes such as regulating signal transduction pathways, neurotransmission, production of neurons and formation of myelin sheath around the axon. It is also associated with the membrane receptor function and synaptic plasticity. DHA supports membrane integrity, fluidity and organization. It is also found to be involved in neuroinflammation. DHA plays a vital role in the development and maturation of the brain. 17(S)-HDHA (hydroxy docosahexaenoic acid) can serve as a precursor for specialized pro-resolving mediators (D-series).
包装
2 mL Amber Glass Sealed Ampule (900125E-100ug)
2 mL Amber Glass Sealed Ampule (900125E-500ug)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
警示用语：
Danger
危险声明
危险分类
Eye Irrit. 2 - Flam. Liq. 2
储存分类代码
3 - Flammable liquids
WGK
WGK 1
闪点(°F)
55.4 °F - closed cup
闪点(°C)
13.0 °C - closed cup
法规信息
危险化学品
此项目有
Principles of Nutrigenetics and Nutrigenomics: Fundamentals of Individualized Nutrition, 460-460 (2019)
Michael J Weiser et al.
Nutrients, 8(2), 99-99 (2016-02-24)
Docosahexaenoic acid (DHA) is the predominant omega-3 (n-3) polyunsaturated fatty acid (PUFA) found in the brain and can affect neurological function by modulating signal transduction pathways, neurotransmission, neurogenesis, myelination, membrane receptor function, synaptic plasticity, neuroinflammation, membrane integrity and membrane organization.
Miaomiao Ruan et al.
Journal of the neurological sciences, 396, 247-253 (2018-12-12)
Glioblastoma (GBM) is a typical malignant tumor, and there are no effective drugs capable of improving patient survival. Docosahexaenoic acid (DHA), a nutrient essential to animal health and neurodevelopment, exerts an anticancer effect in several types of cancer. However, the
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