Product Name
5-PAHSA, 5-(palmitoyloxy)octadecanoic acid, chloroform
表单
liquid
包装
pkg of 1 × 1 mL (900410C-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 900410C
浓度
1 mg/mL (900410C-1mg)
脂质类型
neutral glycerides
neutral lipids
运输
dry ice
储存温度
−20°C
SMILES字符串
CCCCCCCCCCCCCC(OC(CCCCCCCCCCCCCCC)=O)CCCC(O)=O
InChI key
QBGKCWKQYJQHJX-UHFFFAOYSA-N
一般描述
Palmitic acid and hydroxystearic acid (PAHSA) containing (O-acyl)-hydroxy fatty acids are being found in tissues and serum extracts of mouse and human.
应用
5-PAHSA or 5-(palmitoyloxy)octadecanoic acid might be used as (O-acyl)-hydroxy fatty acids (OAHFAs) standard to determine ester position in isomeric OAHFAs by ion trap mass spectrometry. It is also suitable for use as a standard for the quantification of fatty acid esters of hydroxy fatty acids (FAHFAs) by liquid chromatography–mass spectrometry (LC-MS).
生化/生理作用
Palmitic acid and hydroxystearic acid (PAHSA) levels correlate highly with insulin sensitivity and are reduced in adipose tissue and serum of insulin-resistant humans. In adipocytes, PAHSAs signal through G-protein-coupled receptor 120 (GPR120) to enhance insulin-stimulated glucose uptake. PAHSAs are fatty acid esters of hydroxy fatty acids (FAHFAs), which are endogenous lipids with the potential to treat diabetes and inflammation.
包装
5 mL Clear Glass Sealed Ampule (900410C-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system, Liver,Kidney
WGK
WGK 3
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