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Merck
CN

999994C

Avanti

12:0 Diether PC

Avanti Research™ - A Croda Brand

别名:

1,2-di-0-dodecyl-sn-glycero-3-phosphocholine

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关于此项目

经验公式（希尔记法）:
C32H68NO6P
化学文摘社编号:
72593-72-7
分子量:
593.86
UNSPSC代码:
12352211
NACRES:
NA.25

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产品名称

12:0 Diether PC, Avanti Research™ - A Croda Brand 999994C

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 1 mL (999994C-10mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 999994C

浓度

10 mg/mL (999994C-10mg)

脂质类型

phospholipids
cardiolipins

运输

dry ice

储存温度

−20°C

SMILES字符串

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCCCCCC)COCCCCCCCCCCCC)=O

一般描述

12:0 Diether PC (phosphocholine) is a glycerophospholipid having two dodecane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.

应用

12:0 Diether PC or 1,2-di-O-dodecyl-sn-glycero-3-phosphocholine might be used in small micelles for nuclear magnetic resonance (NMR) experiments to study the interaction of peptide with model membranes.

生化/生理作用

12:0 Diether PC (phosphocholine) is found to be a simpler membrane model and is highly compatible with nuclear magnetic resonance (NMR). It is useful in bicelles formation. Bicelles can be integrated into standard crystallization protocols and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.

包装

5 mL Clear Glass Sealed Ampule (999994C-10mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

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分析证书(COA)

Lot/Batch Number

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Interaction of a peptide derived from C-terminus of human TRPA1 channel with model membranes mimicking the inner leaflet of the plasma membrane
Witschas K, et al.
Biochimica et Biophysica Acta - Biomembranes, 1848(5), 1147-1156 (2015)
Structural and functional roles of ether lipids
Dean JM and Lodhi IJ
Protein & cell, 9(2), 196-206 (2018)

商品

Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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