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Merck
CN

999994C

Avanti

12:0 Diether PC

Avanti Research - A Croda Brand

别名:

1,2-di-0-dodecyl-sn-glycero-3-phosphocholine

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关于此项目

经验公式(希尔记法):
C32H68NO6P
化学文摘社编号:
分子量:
593.86
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

12:0 Diether PC, Avanti Research - A Croda Brand 999994C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCCCCCC)COCCCCCCCCCCCC)=O

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (999994C-10mg)

manufacturer/tradename

Avanti Research - A Croda Brand 999994C

concentration

10 mg/mL (999994C-10mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

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General description

12:0 Diether PC (phosphocholine) is a glycerophospholipid having two dodecane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.

Application

12:0 Diether PC or 1,2-di-O-dodecyl-sn-glycero-3-phosphocholine might be used in small micelles for nuclear magnetic resonance (NMR) experiments to study the interaction of peptide with model membranes.

Biochem/physiol Actions

12:0 Diether PC (phosphocholine) is found to be a simpler membrane model and is highly compatible with nuclear magnetic resonance (NMR). It is useful in bicelles formation. Bicelles can be integrated into standard crystallization protocols and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.

Packaging

5 mL Clear Glass Sealed Ampule (999994C-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Interaction of a peptide derived from C-terminus of human TRPA1 channel with model membranes mimicking the inner leaflet of the plasma membrane
Witschas K, et al.
Biochimica et Biophysica Acta - Biomembranes, 1848(5), 1147-1156 (2015)
Structural and functional roles of ether lipids
Dean JM and Lodhi IJ
Protein & cell, 9(2), 196-206 (2018)

商品

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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