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Merck
CN

A-134

对乙酰氨基酚(扑热息痛)I杂质混合物 溶液

25 μg/mL in methanol (each analyte), certified reference material, ampule of 1 mL, Cerilliant®

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关于此项目

UNSPSC Code:
12352200
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grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

25 μg/mL in methanol (each analyte)

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

pharmaceutical (small molecule)

format

multi-component solution

storage temp.

−20°C

General description

Acetaminophen is formed as a metabolic product of phenacetin and is a well-known drug used in the treatment of pain and fever due to its effective central analgesic and antipyretic properties. It is also the only analgesic drug that is non-opioid and available in the oral, rectal, and intravenous formulation forms. It has been posited to inhibit the synthesis of prostaglandins and exhibit a mode of action similar to nonsteroidal anti-inflammatory drugs (NSAIDs).

Application

Acetaminophen Impurity Mixture solution may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany


分析物

说明

  • Acetaminophen Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

  • Acetaminophen Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

  • Acetaminophen Related Compound D, Pharmaceutical Secondary Standard; Certified Reference Material

  • Acetaminophen Related Compound F, Pharmaceutical Secondary Standard; Certified Reference Material

  • Acetaminophen, Pharmaceutical Secondary Standard; Certified Reference Material

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

监管及禁止进口产品

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Intravenous paracetamol (acetaminophen)
Duggan ST and Scott LJ
Drugs, 69(1), 101- 113 (2009)
Acetaminophen poisoning and toxicity
Rumack BH and Matthew H
Pediatrics, 55(6), 871- 876 (1975)
Acetaminophen-induced hepatotoxicity
James LP, et al.
Drug Metabolism and Disposition, 31(12), 1499- 1506 (2003)



全球贸易项目编号

货号GTIN
SML0743-10MG04061837107030
SML0743-50MG04061832723952
69152-5G-F04061833447970
69152-25G-F04061833365496
12122002-1VL04061837343667
MAB8012504053252668128
MABF3046-100UL04065266060188
MABF3046-25UL04065266060195
SAB4504114-100UG04061831455311
MAB1699004053252576737
HLTUD019904061836098148
MSTUD004604061836858018
HLMIR019904061836734282
HLMIR225404061836730321
MLMIR004604061836706777
MLMIR004504061836706760
MLTUD004504061836067700
MLTUD004604061836067717
Z214760-1EA04061832348780
Z406686-1EA04061832349459
Z508616-1EA04061832349992
WHA1045200604061831601084