A-155
乙酰水杨酸酐（阿司匹林杂质F） 溶液
100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®
等级
certified reference material
表单
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
100 μg/mL in acetonitrile
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
pharmaceutical (small molecule)
包装形式
single component solution
储存温度
−20°C
InChI
1S/C18H14O7/c1-11(19)23-15-9-5-3-7-13(15)17(21)25-18(22)14-8-4-6-10-16(14)24-12(2)20/h3-10H,1-2H3
InChI key
OAWXYINGQXLWOE-UHFFFAOYSA-N
一般描述
Acetylsalicylic Anhydride (ASN) is considered to be an immunogenic impurity of aspirin and the allergic reactions to the drug are attributed to the presence of this impurity.
应用
Acetylsalicylic Anhydride (ASN) may be used as a pharmaceutical reference standard for the determination of trace amounts of analyte in aspirin samples and aspirin formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
储存分类代码
3 - Flammable liquids
WGK
WGK 2
闪点(°F)
35.6 °F - closed cup
闪点(°C)
2.0 °C - closed cup
法规信息
新产品
此项目有
Isolation of salicylsalicylic acid, acetylsalicylsalicylic acid, and acetylsalicylic anhydride from aspirin tablets by extraction and high-pressure liquid chromatography
Reepmeyer JC and Kirchhoefer RD
Journal of Pharmaceutical Sciences, 68(9), 1167-1169 (1979)
Quantitative determination by high-performance liquid chromatography of acetylsalicylic acid and related substances in tablets
Verstraeten A, et al.
Journal of Chromatography A, 388(9), 201-216 (1987)
Application of gas-liquid chromatography and high-performance liquid chromatography to the analysis of trace amounts of salicylic acid, acetylsalicylic anhydride and acetylsalicylsalicylic acid in aspirin samples and aspirin formulations
Ali Syed Laik
Journal of Chromatography A, 126, 651-663 (1976)
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