A-155
乙酰水杨酸酐（阿司匹林杂质F） 溶液
100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®
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经验公式（希尔记法）:
C18H14O7
化学文摘社编号:
分子量:
342.30
NACRES:
NA.24
UNSPSC Code:
12352200
MDL number:
InChI
1S/C18H14O7/c1-11(19)23-15-9-5-3-7-13(15)17(21)25-18(22)14-8-4-6-10-16(14)24-12(2)20/h3-10H,1-2H3
InChI key
OAWXYINGQXLWOE-UHFFFAOYSA-N
grade
certified reference material
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
100 μg/mL in acetonitrile
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
pharmaceutical (small molecule)
format
single component solution
storage temp.
−20°C
General description
Acetylsalicylic Anhydride (ASN) is considered to be an immunogenic impurity of aspirin and the allergic reactions to the drug are attributed to the presence of this impurity.
Application
Acetylsalicylic Anhydride (ASN) may be used as a pharmaceutical reference standard for the determination of trace amounts of analyte in aspirin samples and aspirin formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
35.6 °F - closed cup
flash_point_c
2.0 °C - closed cup
法规信息
新产品
此项目有
Isolation of salicylsalicylic acid, acetylsalicylsalicylic acid, and acetylsalicylic anhydride from aspirin tablets by extraction and high-pressure liquid chromatography
Reepmeyer JC and Kirchhoefer RD
Journal of Pharmaceutical Sciences, 68(9), 1167-1169 (1979)
Application of gas-liquid chromatography and high-performance liquid chromatography to the analysis of trace amounts of salicylic acid, acetylsalicylic anhydride and acetylsalicylsalicylic acid in aspirin samples and aspirin formulations
Ali Syed Laik
Journal of Chromatography A, 126, 651-663 (1976)
Quantitative determination by high-performance liquid chromatography of acetylsalicylic acid and related substances in tablets
Verstraeten A, et al.
Journal of Chromatography A, 388(9), 201-216 (1987)
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