A-914
7-氨基硝基安定 溶液
100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
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关于此项目
经验公式（希尔记法）:
C15H13N3O
化学文摘社编号:
分子量:
251.28
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-835-2
MDL number:
InChI key
OYOUQHVDCKOOAL-UHFFFAOYSA-N
InChI
1S/C15H13N3O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9,16H2,(H,18,19)
SMILES string
O=C1NC2=CC=C(N)C=C2C(C3=CC=CC=C3)=NC1
grade
certified reference material
form
liquid
feature
SNAP-N-SPIKE®, SNAP-N-SHOOT®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
100 μg/mL in acetonitrile
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
clinical testing
pharmaceutical (small molecule)
format
single component solution
storage temp.
−20°C
General description
7-Aminonitrazepam is a major urinary metabolite of nitrazepam, a benzodiazepine used to treat insomnia and sold under the trade names Mogadon and Alodorm. This certified solution standard is suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, or urine drug monitoring of nitrazepam use.
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
35.6 °F - closed cup
flash_point_c
2 °C - closed cup
法规信息
监管及禁止进口产品
此项目有
M Tomita et al.
Journal of chromatography, 621(2), 249-255 (1993-11-24)
We applied micellar electrokinetic capillary chromatography to simultaneous separation and determination of nitrazepam and its major metabolites, 7-aminonitrazepam and 7-acetamidonitrazepam, in spiked urine. Prior to electrophoresis, the three compounds were successfully extracted from the spiked urine with commercial disposable solid-phase
High-performance liquid chromatographic determination of nitrazepam and its metabolites in human urine.
T Kozu
Journal of chromatography, 310(1), 213-218 (1984-09-14)
Fumio Moriya et al.
Forensic science international, 131(2-3), 108-112 (2003-02-19)
We report a case of nitrazepam poisoning in which the distribution of nitrazepam and 7-aminonitrazepam was determined in body fluids and tissues. A 52-year-old woman was found dead in a shallow ditch (approximately 5 cm in depth), in the winter.
B J Hart et al.
Methods and findings in experimental and clinical pharmacology, 10(1), 21-26 (1988-01-01)
The stability of some selected benzodiazepines in saliva has been studied. The benzodiazepines nitrazepam and clonazepam were found to be unstable in saliva at room temperature and nitrazepam was converted into 7-aminonitrazepam. The conversion rate of nitrazepam was strongly dependent
Yu Zhu et al.
Se pu = Chinese journal of chromatography, 20(5), 394-397 (2005-12-20)
A highly sensitive method has been developed for the analysis of 7-aminonitrazepam (7-ANIZ), the major metabolite of nitrazepam, in urine by trimethylsilyl derivatization-gas chromatography/mass spectrometry. Urine samples were extracted with ethyl ether-ethyl acetate (99:1, volume ratio). The extracts were derivatized
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