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Merck
CN

B-022

蟾毒色胺 溶液

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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经验公式(希尔记法):
C12H16N2O
化学文摘社编号:
分子量:
204.27
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-835-2
MDL number:
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InChI key

VTTONGPRPXSUTJ-UHFFFAOYSA-N

InChI

1S/C12H16N2O/c1-14(2)6-5-9-8-13-12-4-3-10(15)7-11(9)12/h3-4,7-8,13,15H,5-6H2,1-2H3

SMILES string

OC1=CC=C(NC=C2CCN(C)C)C2=C1

grade

certified reference material

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule D (Switzerland); Decreto Lei 15/93: Tabela IIA (Portugal)

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

General description

蟾毒色胺是一种致幻生物碱,存在于蘑菇,植物,哺乳动物和属于蟾蜍属的蟾蜍中。这种药物在结构上类似于蘑菇中发现的迷幻化合物psilocin。 该Snap-N-Spike®对照溶液适用于通过LC-MS/MS或GC/MS进行尿液药物检测、临床毒理学或法医分析。

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

法规信息

危险化学品
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B L Roth et al.
Molecular pharmacology, 52(2), 259-266 (1997-08-01)
Several models of agonist binding to G protein-coupled 5-hydroxytryptamine [5-HT] (serotonin) receptors have highlighted the potential importance of highly conserved aromatic residues for ligand binding and agonist efficacy. In this study, we tested these models by constructing and characterizing a
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Journal of ethnopharmacology, 106(2), 198-202 (2006-02-04)
This paper is the first thorough analysis of takini, a hallucinogen used by the shamans of several peoples in Suriname, French Guiana, and the region east of the Para in Brazil. The drug is contained in the latex of the
K A Berg et al.
Molecular pharmacology, 54(1), 94-104 (1998-07-11)
There are many examples of a single receptor coupling directly to more than one cellular signal transduction pathway. Although traditional receptor theory allows for activation of multiple cellular effectors by agonists, it predicts that the relative degree of activation of
B L Roth et al.
The Journal of pharmacology and experimental therapeutics, 280(2), 576-583 (1997-02-01)
In this study, the relationship between high-affinity agonist binding and second messenger production was examined at native and mutant 5-hydroxytryptamine2A receptors. At native 5-hydroxytryptamine2A receptors all agonists, with the exception of quipazine, discriminated between high- and low-affinity states of the
Barbara J Ebersole et al.
Molecular pharmacology, 63(1), 36-43 (2002-12-19)
Based on experiment and computational simulation, we present a structural explanation for the differing efficacies of indole agonists at the human serotonin 5-HT2A receptor (5HT2AR). We find that serotonin [5-hydroxytryptamine (5-HT)] forms hydrogen-bonds with Ser3.36 in helix 3 and Ser5.46

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