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Merck
CN

C-175

咖啡因杂质混合物 溶液

0.04-2.0 mg/mL (50:50 Acetonitrile:Water (v/v)), certified reference material, ampule of 1 mL, Cerilliant®

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经验公式（希尔记法）:
C7H8N4O2
分子量:
180.16
NACRES:
NA.24
UNSPSC Code:
41116107

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产品名称

咖啡因杂质混合物 溶液, 0.04-2.0 mg/mL (50:50 Acetonitrile:Water (v/v)), certified reference material, ampule of 1 mL, Cerilliant®

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

composition

Caffeine
Caffeine
2-(Tert-Butylamino)-3′-Bromopropiophenone Hydrochloride
2-(Tert-Butylamino)-3′-Bromopropiophenone Hydrochloride, 2 mg/mL
1,7-Dimethyl-3,7-dihydro-1H-purine-2,6-dione(Caffeine Imp F)
Theobromine (Caffeine RCD)
Caffeine
2-(Tert-Butylamino)-3′-Bromopropiophenone Hydrochloride
2-(Tert-Butylamino)-3′-Bromopropiophenone Hydrochloride, 40 μg/mL
Theobromine (Caffeine Imp D)
Theobromine (Caffeine RCD)
Caffeine
2-(Tert-Butylamino)-3′-Bromopropiophenone Hydrochloride
2-(Tert-Butylamino)-3′-Bromopropiophenone Hydrochloride, 40 μg/mL
Theophylline (Caffeine Imp A)
Caffeine
2-(Tert-Butylamino)-3′-Bromopropiophenone Hydrochloride
2-(Tert-Butylamino)-3′-Bromopropiophenone Hydrochloride, 40 μg/mL
1,3,9-Trimethyl-3,9-dihydro-1H-purine-2,6-dione(Caffeine Imp C)
Caffeine
2-(Tert-Butylamino)-3′-Bromopropiophenone Hydrochloride
2-(Tert-Butylamino)-3′-Bromopropiophenone Hydrochloride, 40 μg/mL

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

0.04-2.0 mg/mL (50:50 Acetonitrile:Water (v/v))

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

pharmaceutical (small molecule)

format

multi-component solution

storage temp.

−20°C

Application

Caffeine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Caffeine is a naturally occurring compound that is reported to be found in about 60 plant species. It is consumed in different forms such as coffee, tea, cacao powder, and other food and beverages. It is an ergogenic aid because of its ability to enhance the mental and physical performance of athletes during training and competitions. It has been shown to exhibit structural similarities to adenosine and therefore acts by inhibiting the adenosine receptors located on the cell membranes and blocking their activity. It also raises the level of adrenaline in the body which leads to the ergogenic action.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Repr. 1B

存储类别

3 - Flammable liquids

wgk

WGK 3

flash_point_f

48.2 °F

flash_point_c

9 °C

法规信息

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Caffeine and exercise
Graham TE
Sports Medicine (Auckland, N.Z.), 31(11), 785-807 (2001)
Caffeine and adenosine
Ribeiro JA and Sebastiao AM
Journal of Alzheimer'S Disease, 20(s1), S3-S15 (2010)
Caffeine consumption
Barone JJ and Roberts HR
Food And Chemical Toxicology, 34(1), 119-129 (1996)
Caffeine
USP42-NF37
United States Pharmacopeia/National Formulary, 34(5), 645-645 (2018)

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