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Merck
CN

H-087

25-羟基维生素D2标准液 CRM 溶液

5 μg/mL in ethanol, ampule of 1 mL, certified reference material, Cerilliant®

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经验公式(希尔记法):
C28H44O2
化学文摘社编号:
分子量:
412.65
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-578-6
MDL number:
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InChI key

KJKIIUAXZGLUND-ICCVIKJNSA-N

InChI

1S/C28H44O2/c1-19-10-14-24(29)18-23(19)13-12-22-8-7-17-28(6)25(15-16-26(22)28)20(2)9-11-21(3)27(4,5)30/h9,11-13,20-21,24-26,29-30H,1,7-8,10,14-18H2,2-6H3/b11-9+,22-12+,23-13-/t20-,21+,24+,25-,26+,28-/m1/s1

SMILES string

CCCC(O)CC.CC(\C=C\C(C)C(C)(C)O)C1CCC2C(CCCC12C)\C=C\C=C/C=C

grade

certified reference material

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

5 μg/mL in ethanol

format

single component solution

storage temp.

−70°C

General description

A Certified Spiking Solution® of 25-Hydroxyvitamin D2, a prohormone whose blood serum levels are used to determine Vitamin D nutritional status. This solution standard is suitable for critical quantitative applications in research and clinical environments including: for use in preparation of controls and calibrators for LC/UV and LC-MS/MS assays; as system tuning/suitability standards; linearity verification; internal proficiency testing; and for OEM use in preparation of reagents, development of assays and instrument IQ/OQ.

The stable, quantitative solution format provides significant benefits to the user including material savings, increased efficiency of labor, and convenience of use. The shelf stable Snap-N-Spike® format allows laboratories to eliminate painstaking weighing operations and provides the ability to spike a known concentration of analyte into their matrix of choice just before use.

Application

25-Hydroxyvitamin D2 may be used as a certified reference material (CRM) for the determination of the analyte in biological samples by chromatography techniques.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

存储类别

3 - Flammable liquids

wgk

WGK 1

flash_point_f

57.2 °F - closed cup

flash_point_c

14 °C - closed cup

法规信息

危险化学品
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Paul Haggarty et al.
The British journal of nutrition, 109(5), 898-905 (2012-11-22)
The aims of the present study were to determine compliance with current advice on vitamin D and to assess the influence of season, dietary intake, supplement use and deprivation on vitamin D status in pregnant mothers and newborns in the
Kevin D Cashman et al.
The British journal of nutrition, 112(2), 193-202 (2014-05-02)
It has been suggested that vitamin D₂ is not very prevalent in the human food chain. However, data from a number of recent intervention studies suggest that the majority of subjects had measurable serum 25-hydroxyvitamin D₂ (25(OH)D₂) concentrations. Serum 25(OH)D₂
Development and validation of an LC--MS/MS based method for quantification of 25 hydroxyvitamin D2 and 25 hydroxyvitamin D3 in human serum and plasma
Zhang SW, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 961(1), 62-70 (2014)
Anna-Maija Tolppanen et al.
Epidemiology (Cambridge, Mass.), 24(2), 310-319 (2013-02-05)
Higher serum total 25-hydroxyvitamin D (25(OH)D) concentrations have been associated with better lung function and lower risk of allergic disease. 25(OH)D3 constitutes the majority of total 25(OH)D and has been suggested to be more potent than 25(OH)D2. We studied the
Zengliu Su et al.
Clinica chimica acta; international journal of clinical chemistry, 417, 62-66 (2012-12-26)
The circulating form of vitamin D, 25-Hydroxyvitamin D (25-OHD), is commonly measured in clinical labs to evaluate vitamin D status of an individual. Vitamin D exists in 2 major forms: vitamin D3 and D2. Current methodologies for 25-OHD testing include

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Vitamin D deficiency affects bone health, highlighting its vital role in calcium absorption and bone growth.

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