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Merck
CN

IMPC-051-03

副黄嘌呤标准液 CRM 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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关于此项目

经验公式(希尔记法):
C7H8N4O2
化学文摘社编号:
分子量:
180.16
NACRES:
NA.24
UNSPSC Code:
41116107
EC Number:
200-659-6
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grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

room temp

SMILES string

CN1C(=O)Nc2ncn(C)c2C1=O

InChI

1S/C7H8N4O2/c1-10-3-8-5-4(10)6(12)11(2)7(13)9-5/h3H,1-2H3,(H,9,13)

InChI key

QUNWUDVFRNGTCO-UHFFFAOYSA-N

General description

副黄嘌呤是咖啡因的一种主要血浆和尿液代谢产物。该黄嘌呤衍生物同咖啡因一样是中枢神经系统的兴奋剂。这种Snap-N-Spike®参考溶液适用于临床毒理学中的咖啡因定量,或通过LC-MS/MS或GC/MS进行尿液药物检测。

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

危险化学品

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Rebeca Pinhancos et al.
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To investigate the utility of metrics of CYP1A2 activity using caffeine as a probe, and saliva and plasma sampling with or without a 24-h caffeine abstinence. This was a cross-over pharmacokinetic study in 30 healthy male subjects who received a
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Basic & clinical pharmacology & toxicology, 112(4), 257-263 (2012-11-22)
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Handbook of experimental pharmacology, (200)(200), 33-91 (2010-09-23)
Caffeine, theophylline, theobromine, and paraxanthine administered to animals and humans distribute in all body fluids and cross all biological membranes. They do not accumulate in organs or tissues and are extensively metabolized by the liver, with less than 2% of
Samanta Yubero-Lahoz et al.
Drug metabolism and pharmacokinetics, 27(6), 605-613 (2012-06-08)
3,4-Methylenedioxymethamphetamine (MDMA; ecstasy) is a ring-substituted amphetamine widely used for recreational purposes. MDMA is predominantly O-demethylenated in humans by cytochrome P450 (CYP) 2D6, and is also a potent mechanism-based inhibitor of the enzyme. After assessing the inhibition and recovery of

全球贸易项目编号

货号GTIN
IMPC-051-03-1ML04061833865996

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