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Merck
CN

O-021

Supelco

奥美拉唑

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

别名:

5-甲氧基-2 - [[（4-甲氧基-3，5-二甲基-2-吡啶基）甲基]亚磺酰基] -1H-苯并咪唑, Antra, Losec

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关于此项目

经验公式（希尔记法）:
C17H19N3O3S
化学文摘社编号:
73590-58-6
分子量:
345.42
EC 号:
200-659-6
MDL编号:
MFCD00083192
UNSPSC代码:
41116107
PubChem化学物质编号:
329818828
NACRES:
NA.24

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等级

certified reference material

表单

liquid

特点

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

浓度

1.0 mg/mL in methanol

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

pharmaceutical (small molecule)

包装形式

single component solution

储存温度

−20°C

SMILES字符串

COc1ccc2[nH]c(nc2c1)S(=O)Cc3ncc(C)c(OC)c3C

InChI

1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)

InChI key

SUBDBMMJDZJVOS-UHFFFAOYSA-N

基因信息

human ... ATP4A(495), ATP4B(496)

一般描述

Omeprazole, sold under the trade name Prilosec®, is a proton pump inhibitor used in the treatment of peptic ulcers and GERD. This Snap-N-Spike® reference solution is applicable for use in clinical toxicology or forensic analysis by LC-MS/MS or GC/MS.

法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Prilosec is a registered trademark of Astrazeneca AB
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes,Central nervous system

储存分类代码

3 - Flammable liquids

WGK

WGK 2

闪点(°F)

49.5 °F - closed cup

闪点(°C)

9.7 °C - closed cup

法规信息

危险化学品
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V A Zolotarev et al.
Bulletin of experimental biology and medicine, 154(4), 415-418 (2013-03-15)
Proton pump inhibitors were shown to affect the sensitivity of the gastric mucosa to chemical agents. This effect is associated with inhibition of proton back-diffusion and increase in the permeability of the gastric epithelium. We studied the effect of omeprazole
[Comment of the Delphi Care editors on Critical evaluation of interaction screening software available in pharmacies].
Daniel Duh et al.
Journal de pharmacie de Belgique, (4)(4), 14-15 (2013-01-29)
J Labenz et al.
MMW Fortschritte der Medizin, 154 Suppl 4, 110-114 (2013-01-19)
Heartburn and acid regurgitation--cardinal symptoms of gastro-esophageal reflux disease (GERD)--rank among the most frequent gastrointestinal disorders. The high degree of suffering often requires a fast and effective symptom relief. Proton pump inhibitors (PPI) are the medication of choice for all
Z Liu et al.
Drug research, 63(7), 370-375 (2013-04-06)
The present study was conducted to describe the pharmacokinetic profile of immediate-release compound omeprazole capsule and compare it with the enteric-coated formulation under fasting and fed condition.This study was designed to phase I, open-label, randomized, 3-part clinical trial. 12 subjects
James G Sanders et al.
The New Zealand medical journal, 125(1366), 68-73 (2012-12-21)
We present an atypical case of subglottic stenosis with diffuse tracheal stenoses in a child responsive only to steroid and azithromycin (AZI) therapy. A 12-year-old boy presented with acute biphasic stridor on the background of an 18-month history of progressive
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