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Merck
CN

O-021

奥美拉唑

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

别名:

5-甲氧基-2 - [[（4-甲氧基-3，5-二甲基-2-吡啶基）甲基]亚磺酰基] -1H-苯并咪唑, Antra, Losec

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关于此项目

经验公式（希尔记法）:
C17H19N3O3S
化学文摘社编号:
73590-58-6
分子量:
345.42
NACRES:
NA.24
PubChem Substance ID:
329818828
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
MFCD00083192

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InChI key

SUBDBMMJDZJVOS-UHFFFAOYSA-N

InChI

1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)

SMILES string

COc1ccc2[nH]c(nc2c1)S(=O)Cc3ncc(C)c(OC)c3C

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

−20°C

Gene Information

human ... ATP4A(495), ATP4B(496)

General description

Omeprazole, sold under the trade name Prilosec®, is a proton pump inhibitor used in the treatment of peptic ulcers and GERD. This Snap-N-Spike® reference solution is applicable for use in clinical toxicology or forensic analysis by LC-MS/MS or GC/MS.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Prilosec is a registered trademark of Astrazeneca AB
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

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James G Sanders et al.
The New Zealand medical journal, 125(1366), 68-73 (2012-12-21)
We present an atypical case of subglottic stenosis with diffuse tracheal stenoses in a child responsive only to steroid and azithromycin (AZI) therapy. A 12-year-old boy presented with acute biphasic stridor on the background of an 18-month history of progressive
K O Dvorshchenko et al.
Ukrains'kyi biokhimichnyi zhurnal (1999 ), 85(2), 68-77 (2013-07-03)
The intensity of free-radical processes upon long-term omeprazole-induced hypoacidity in the rat pancreas was investigated. Significant violation of oxidative-antioxidative balance in pancreatic tissue upon gastric hypochlorhydria was established: overproduction of superoxide anion, quantitative changes of lipid functional groups, increased level
Aydin Seref Köksal et al.
Acta gastro-enterologica Belgica, 76(1), 34-37 (2013-05-09)
Bismuth-containing quadruple therapy given four times a day is effective in the first-line treatment of Helicobacter pylori. We aimed to investigate whether twice daily posology could eradicate H. pylori at a comparable rate in an area with a high prevalence
E A Sorokina et al.
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, (5)(5), 14-21 (2013-02-14)
The estimation of gastric contents pH and gastroduodenal zone mucous membrane condition based on the fibrogastroduodenoscopy data of40 patients who were examined and received proton pump inhibitors in the postoperative period after heart surgical intervention. It was estimated, that acidic
[Comment of the Delphi Care editors on Critical evaluation of interaction screening software available in pharmacies].
Daniel Duh et al.
Journal de pharmacie de Belgique, (4)(4), 14-15 (2013-01-29)
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