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Merck
CN

W-003

Warfarin solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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经验公式(希尔记法):
C19H16O4
化学文摘社编号:
分子量:
308.33
UNSPSC Code:
41116107
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产品名称

Warfarin solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

InChI

1S/C19H16O4/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22/h2-10,15,17H,11H2,1H3

InChI key

FQEPJUOLUDFINX-UHFFFAOYSA-N

SMILES string

CC(=O)CC(C1C(=O)Oc2ccccc2C1=O)c3ccccc3

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

2-8°C

General description

Warfarin is an anticoagulant sold under the trade names Coumadin® and Jantoven®. Warfarin is also used a pesticide, most often as rat poison. This Snap-N-Spike® reference solution is applicable for use in clinical toxicology, forensic analysis, therapeutic drug monitoring or environmental monitoring and diagnostic testing applications by LC-MS/MS or GC/MS

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Coumadin is a registered trademark of Bristol-Myers Squibb Co.
Jantoven is a registered trademark of Upsher-Smith Laboratories, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Repr. 1A - STOT RE 2

target_organs

Blood

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

法规信息

危险化学品
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[Vascular calcification: a common but overlooked condition].
Peter Stenvinkel
Lakartidningen, 110(21), 1041-1044 (2013-06-29)
Rapid resolution of acute subdural hematoma in a coagulopathic patient.
Navjot Chaudhary et al.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 40(4), 599-600 (2013-06-22)
Ask the doctors. I thought one of the reasons to receive a heart valve made from cow tissue was that you don't have to take blood thinners. Now my doctor is telling me that I will need to take warfarin [Coumadin] for several months after I have my aortic valve replaced. Has the thinking changed?
Thomas Lee et al.
Harvard heart letter : from Harvard Medical School, 23(7), 2-2 (2013-08-07)
Continuing antithrombotics advised for stroke survivors during certain procedures.
Mike Mitka
JAMA, 309(24), 2537-2537 (2013-06-27)
Apixaban [corrected] and warfarin go head to head in selected adults with venous thromboembolism.
BMJ (Clinical research ed.), 347, f4292-f4292 (2013-07-05)

商品

Comparative analysis of Supel™ BioSPME 96-Pin device with a rapid equilibrium dialysis technique for accuracy of measured values, sample cleanliness, and workflow time in drug protein binding.

实验方案

HPLC Analysis of Warfarin™ Anticoagulant on Ascentis® C18

This study demonstrates the analysis of Warfarin in plasma samples utilizing chiral and achiral (reversed-phase) LC-MS and effective sample prep to remove endogenous phospholipids

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