方案
≥97% (HPLC)
质量水平
表单
lyophilized solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated (hygroscopic)
颜色
white to off-white
溶解性
5% acetic acid: 1 mg/mL
water: 1 mg/mL
运输
ambient
储存温度
−20°C
InChI
1S/C17H30N8O9/c18-5-11(27)23-8(2-1-3-21-17(19)20)14(31)22-6-12(28)24-9(4-13(29)30)15(32)25-10(7-26)16(33)34/h8-10,26H,1-7,18H2,(H,22,31)(H,23,27)(H,24,28)(H,25,32)(H,29,30)(H,33,34)(H4,19,20,21)/t8-,9-,10-/m0/s1
InChI key
RGNVSYKVCGAEHK-GUBZILKMSA-N
一般描述
A cell binding protein domain. Competitively inhibits direct binding of fibroblasts to fibronectin. In mice it has been shown to prevent bladder tumor cell implantation. Also, reported to inhibit the migration of vascular smooth muscle cells into fibrin gels.
生化/生理作用
Cell permeable: no
Primary Target
fibroblast binding
fibroblast binding
Product does not compete with ATP.
Reversible: no
外形
Supplied as an acetate salt.
制备说明
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Kodama, M., et al. 2002. Life Sci.71, 1139.
Hyacinthe, L.M., et al. 1995. Ann. Surg. Oncol.2, 450.
Pierschbacher, M.D., and Ruoslahti, E. 1984. Nature309, 30.
Hyacinthe, L.M., et al. 1995. Ann. Surg. Oncol.2, 450.
Pierschbacher, M.D., and Ruoslahti, E. 1984. Nature309, 30.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Standard Handling (A)
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