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Merck
CN

04-811

Sigma-Aldrich

Anti-phospho-eNOS/NOS III (Thr495) Antibody, rabbit monoclonal

culture supernatant, Upstate®

别名:

NOS III, endothelial nitric oxidase synthase, endothelial nitric oxide synthase, nitric oxide synthase 3 (endothelial cell)

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关于此项目

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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生物来源

rabbit

质量水平

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

monoclonal

种属反应性

bovine

制造商/商品名称

Upstate®

技术

western blot: suitable

同位素/亚型

IgG

NCBI登记号

UniProt登记号

运输

dry ice

靶向翻译后修饰

phosphorylation (pThr495)

基因信息

mouse ... Nos3(287024)

一般描述

135 kDa

免疫原

Peptide containing the sequence KK[pT]FK in which pT corresponds to phosphothreonine at residue 495 of human eNOS/NOS III

应用

This Anti-phospho-eNOS/NOS III (Thr495) Antibody is validated for use in WB for the detection of phospho-eNOS/NOS III (Thr495).
Western Blot Analysis:
A 1:2,000-1:10,000 dilution of this lot detected phosphorylated eNOS/NOS III in fetal bovine heart endothelial cell lysate.

生化/生理作用

Predicted cross-reactivity with human, rabbit, mouse and rat
Recognizes phosphorylated eNOS/NOS III.

外形

Cultured supernatant in 0.05% sodium azide

分析说明

Control
Fetal bovine heart endothelial cell lysate
routinely evaluated by immunoblot on fetal bovine heart endothelial cell lysate

其他说明

Replaces: 05-811

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Novel protective role of endogenous cardiac myocyte P2X4 receptors in heart failure.
Yang, T; Shen, JB; Yang, R; Redden, J; Dodge-Kafka, K; Grady, J; Jacobson, KA; Liang, BT
Circulation. Heart Failure null
A P S Mesquita et al.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 55, e11612-e11612 (2022-02-10)
Anoikis is a type of apoptosis that occurs in response to the loss of adhesion to the extracellular matrix (ECM). Anoikis resistance is a critical mechanism in cancer and contributes to tumor metastasis. Nitric oxide (NO) is frequently upregulated in
Martina Monti et al.
The Journal of pharmacology and experimental therapeutics, 351(3), 500-509 (2014-09-23)
At the cardiovascular level, nitric oxide (NO) controls smooth muscle functions, maintains vascular integrity, and exerts an antihypertensive effect. Metal-nonoates are a recently discovered class of NO donors, with NO release modulated through the complexation of the N-aminoethylpiperazine N-diazeniumdiolate ligand

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