Anti-trimethyl Histone H3 (Lys27) Antibody, clone 18E9.1, Alexa Fluor^™ 488 Conjugate

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

17 kDa calculated

Linear peptide corresponding to trimethyl Histone H3 (Lys27).

Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected trimethyl Histone H3 (Lys27) in NIH/3T3 cells.

Research Category
Epitope Tags & General Use

Research Sub Category
Epitope Tags

This Anti-trimethyl Histone H3 (Lys27) Antibody, clone 18E9.1, Alexa Fluor^™ 488 Conjugate is validated for use in ICC for the detection of trimethyl Histone H3 (Lys27).

Protein G Purified

Purified mouse conjugate in buffer containing PBS, 15 mg/ml BSA, and 0.1% Sodium Azide.

Stable for 1 year at 2-8°C from date of receipt.

Evaluated by Immunocytochemistry Analysis in HepG2 cells

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected trimethyl Histone H3 (Lys27) in HepG2 cells.

Alexa Fluor^™ is a registered trademark of Life Technologies.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

ALEXA FLUOR is a trademark of Life Technologies

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