05-505
Anti-IQGAP2 Antibody, clone BB9
ascites fluid, clone BB9, Upstate®
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
BB9, monoclonal
Application:
IP, WB
Citations:
6
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
BB9, monoclonal
Gene Information
human ... IQGAP2(10788)
species reactivity
mouse, human
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
General description
180kDa
Immunogen
GST-fusion protein corresponding to residues 519-939 of human IQGAP2, purified from E. coli
Application
Anti-IQGAP2 Antibody, clone BB9 detects level of IQGAP2 & has been published & validated for use in IP & WB.
Biochem/physiol Actions
IQGAP2, not IQGAP1
Analysis Note
routinely evaluated by immunoblot on RIPA lysates from HepG2 cells
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
J A Epp et al.
Current biology : CB, 7(12), 921-929 (1998-02-21)
Proteins of the IQGAP family have been identified as candidate effectors for the Rho family of GTPases; however, little is known about their cellular functions. The domain structures of IQGAP family members make them excellent candidates as regulators of the
Paclitaxel induces pyroptosis by inhibiting the volumea?`sensitive chloride channel leucinea?`rich repeata?`containing 8a in ovarian cancer cells.
Yang, et al.
Oncology Reports, 49 (2023)
Jacquelyn A Gorman et al.
Journal of immunology (Baltimore, Md. : 1950), 188(12), 6135-6144 (2012-05-11)
The Ras GTPase-activating-like protein IQGAP1 is a multimodular scaffold that controls signaling and cytoskeletal regulation in fibroblasts and epithelial cells. However, the functional role of IQGAP1 in T cell development, activation, and cytoskeletal regulation has not been investigated. In this
Metabolic adaptation to a disruption in oxygen supply during myocardial ischemia and reperfusion is underpinned by temporal and quantitative changes in the cardiac proteome.
Xin Li,Fatih Arslan,Yan Ren,Sunil S Adav,Kian Keong Poh,Vitaly Sorokin,Chuen Neng Lee et al.
Journal of Proteome Research null
Jung Eun Park et al.
Molecular & cellular proteomics : MCP, 9(6), 1085-1099 (2010-02-04)
Under hypoxia, tumor cells produce a secretion that modulates their microenvironment to facilitate tumor angiogenesis and metastasis. Here, we observed that hypoxic or reoxygenated A431 carcinoma cells exhibited enhanced angiogenic and metastatic potential such as reduced cell-cell and cell-extracellular matrix
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