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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
2D3, monoclonal
Species reactivity:
human, mouse, rat
Application:
electrophoretic mobility shift assay
western blot
western blot
Technique(s):
electrophoretic mobility shift assay: suitable
western blot: suitable
western blot: suitable
Citations:
14
Uniprot accession no.:
产品名称
抗磷酸化-GSK3β(Ser9)抗体,克隆2D3, clone 2D3, Upstate®, from mouse
biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
2D3, monoclonal
species reactivity
human, mouse, rat
manufacturer/tradename
Upstate®
technique(s)
electrophoretic mobility shift assay: suitable
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pSer9)
Quality Level
Gene Information
human ... GSK3B(2932)
Analysis Note
通过免疫印迹对IGF-1刺激的L6细胞进行常规评估
Application
抗磷酸化GSK3β(Ser9)抗体,克隆2D3是用于EMSA & WB的抗磷酸化GSK3β(Ser9)抗体。
研究子类别
PI3K、Akt & mTOR信号传导
PI3K、Akt & mTOR信号传导
研究类别
信号传导
信号传导
Biochem/physiol Actions
GSK3beta
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
46kDa (GSK3β)和51kDa (GSK3α)
Immunogen
对应于人GSK3beta氨基酸6-12(RTT[pS]AE)的肽
Other Notes
替代:04-1075
Physical form
亲硫吸附色谱
将100 µg亲硫蛋白和分子排阻色谱法纯化的小鼠IgG1κ溶于100 µL抗体储存缓冲液(含PEG、蔗糖和0.09%叠氮化钠的PBS)和50%甘油中。
形式:纯化
Preparation Note
在-20°C下可保存2年
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
Pei-Wen Cheng et al.
Biomedicines, 9(11) (2021-11-28)
Traumatic brain injury confers a significant and growing public health burden. It is a major environmental risk factor for dementia. Nonetheless, the mechanism by which primary mechanical injury leads to neurodegeneration and an increased risk of dementia-related diseases is unclear.
Hui Sheng et al.
International journal of medical sciences, 10(6), 782-789 (2013-05-01)
We previously reported that the constitutional flavonoid glycosides derived from herb Epimedium (EF, composed of seven flavonoid compounds with common nuclear stem) exerted beneficial effects on the bone, including promoting bone formation and inhibiting bone marrow fat deposition. Recent in
Tzyy-Yue Wong et al.
Journal of clinical medicine, 7(11) (2018-11-08)
The dynamics of a living body enables organs to experience mechanical stimulation at cellular level. The human cardiomyocytes cell line provides a source for simulating heart dynamics; however, a limited understanding of the mechanical stimulation effect on them has restricted
Yu-Te Lin et al.
Journal of clinical medicine, 7(10) (2018-10-12)
Recent studies have indicated that several anti-hypertensive drugs may delay the development and progression of Alzheimer's disease (AD). However, the relationships among AD, hypertension, and oxidative stress remain to be elucidated. Here, we aimed to determine whether reactive oxygen species
Laia Lidón et al.
International journal of molecular sciences, 22(10) (2021-06-03)
Tau protein is largely responsible for tauopathies, including Alzheimer's disease (AD), where it accumulates in the brain as insoluble aggregates. Tau mRNA is regulated by alternative splicing, and inclusion or exclusion of exon 10 gives rise to the 3R and
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