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Merck
CN

05-799

Anti-Beta (β)-Amyloid antibody

UPSTATE®, mouse monoclonal, 11A5-B10

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关于此项目

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
11A5-B10, monoclonal
Species reactivity:
human, mouse
Application:
IHC, WB
Citations:
2
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产品名称

Anti-Amyloid β (Aβ)x-40 Antibody, clone 11A5-B10, ascites fluid, clone 11A5-B10, Upstate®

biological source

mouse

antibody form

ascites fluid

antibody product type

primary antibodies

clone

11A5-B10, monoclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable, western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

Gene Information

human ... APP(351)

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General description

~4.5kDa

Immunogen

peptide corresponding to amino acids 34-40 of human Amyloid βx-40 peptide

Application

Detect Amyloid β (Aβ)x-40 using this Anti-Amyloid β (Aβ)x-40 Antibody, clone 11A5-B10 validated for use in WB, IH.

Biochem/physiol Actions

Amyloid βx-40 polypeptide

Analysis Note

routinely evaluated by immunoblot on of synthetic Amyloid βx-40 polypeptide

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Yuta Takaichi et al.
Acta neuropathologica communications, 9(1), 10-10 (2021-01-09)
Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β (Aβ) as senile plaques and cerebral amyloid angiopathy, and hyperphosphorylated tau (hp-tau) as neurofibrillary tangles in the brain. The AD-related pathology has been reported in several non-human animals, and most
Céline Vrancx et al.
Molecular neurobiology, 58(12), 6647-6669 (2021-10-06)
The β-amyloid peptide (Aβ) is found as amyloid fibrils in senile plaques, a typical hallmark of Alzheimer's disease (AD). However, intermediate soluble oligomers of Aβ are now recognized as initiators of the pathogenic cascade leading to AD. Studies using recombinant

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