产品名称
Anti-Amyloid β (Aβ)x-40 Antibody, clone 11A5-B10, ascites fluid, clone 11A5-B10, Upstate®
biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
11A5-B10, monoclonal
species reactivity
human, mouse
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Gene Information
human ... APP(351)
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General description
~4.5kDa
Immunogen
peptide corresponding to amino acids 34-40 of human Amyloid βx-40 peptide
Application
Detect Amyloid β (Aβ)x-40 using this Anti-Amyloid β (Aβ)x-40 Antibody, clone 11A5-B10 validated for use in WB, IH.
Biochem/physiol Actions
Amyloid βx-40 polypeptide
Analysis Note
routinely evaluated by immunoblot on of synthetic Amyloid βx-40 polypeptide
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Yuta Takaichi et al.
Acta neuropathologica communications, 9(1), 10-10 (2021-01-09)
Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β (Aβ) as senile plaques and cerebral amyloid angiopathy, and hyperphosphorylated tau (hp-tau) as neurofibrillary tangles in the brain. The AD-related pathology has been reported in several non-human animals, and most
Céline Vrancx et al.
Molecular neurobiology, 58(12), 6647-6669 (2021-10-06)
The β-amyloid peptide (Aβ) is found as amyloid fibrils in senile plaques, a typical hallmark of Alzheimer's disease (AD). However, intermediate soluble oligomers of Aβ are now recognized as initiators of the pathogenic cascade leading to AD. Studies using recombinant
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