05-809
Anti-trimethyl (Lys9)-phospho (Ser10)-Histone H3 Antibody, rabbit monoclonal
Upstate®, from rabbit
别名:
H3K9me3S10P, Histone H3 (tri methyl K9, phospho S10)
产品名称
Anti-trimethyl (Lys9)-phospho (Ser10)-Histone H3 Antibody, rabbit monoclonal, Upstate®, from rabbit
biological source
rabbit
antibody form
purified antibody
antibody product type
primary antibodies
clone
monoclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
inhibition assay: suitable (peptide)
multiplexing: suitable
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pSer10), trimethylation (Lys9)
Quality Level
Gene Information
human ... H3C1(8350)
Application
Anti-trimethyl (Lys9)-phospho (Ser10)-Histone H3 Antibody is a rabbit monoclonal antibody for detection of trimethyl (Lys9)-phospho (Ser10)-Histone H3 also known as H3K9me3S10P, has been validated in WB, PIA, Mplex.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
Biochem/physiol Actions
Broad species cross-reactivity is expected
trimethyl (Lys9)-phospho (Ser10)-histone H3
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Mr 17kDa
Immunogen
KLH-conjugated, synthetic peptide containing the sequenc...ARme3KpS... in which me3K corresponds to trimethyl-lysine 9 and pS to phosphoserine 10 of human histone H3
Physical form
0.2M Tris-glycine, pH 7.4, 0.15M NaCl, 100mM EDTA, 0.05% sodium azide, before the addition of glycerol to 30%
Format: Purified
Protein A purified
Preparation Note
Stable for 2 years at -20°C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
Scott B Rothbart et al.
Molecular cell, 59(3), 502-511 (2015-07-28)
Access to high-quality antibodies is a necessity for the study of histones and their posttranslational modifications (PTMs). Here we debut the Histone Antibody Specificity Database (http://www.histoneantibodies.com), an online and expanding resource cataloging the behavior of widely used, commercially available histone
Meng Wang et al.
Cancer research, 74(10), 2825-2834 (2014-03-22)
Therapeutics that target the epidermal growth factor receptor (EGFR) can enhance the cytotoxic effects of ionizing radiation (IR). However, predictive genomic biomarkers of this radiosensitization have remained elusive. By screening 40 non-small cell lung cancer cell (NSCLC) lines, we established
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