产品名称
抗-T 细胞受体抗体（克隆 C305）, culture supernatant, clone C305, Upstate®
biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
C305, monoclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable
multiplexing: suitable
isotype
IgM
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TRDD3(28523)
Analysis Note
常规用于生物测定，用于激活Jurkat细胞中的T细胞受体信号级联
Application
抗-T细胞受体抗体（克隆C305）可检测T细胞受体的水平 &已有相关文献发表&经过验证可用于Mplex & IP。
研究子类别
免疫球蛋白 & 免疫学
免疫球蛋白 & 免疫学
研究类别
炎症 & 免疫学
炎症 & 免疫学
Biochem/physiol Actions
Jurkat T细胞受体
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Immunogen
Jurkat T细胞
Physical form
浓缩的培养上清液。
Preparation Note
自运送之日起在-20°C下稳定保存2年
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Nadia Martinez-Martin et al.
Nature communications, 7, 11473-11473 (2016-05-06)
Viruses encode secreted and cell-surface expressed proteins essential to modulate host immune defenses and establish productive infections. However, to date there has been no systematic study of the extracellular interactome of any human virus. Here we utilize the E3 proteins
Pussadee Paensuwan et al.
Journal of immunology (Baltimore, Md. : 1950), 196(1), 448-458 (2015-11-22)
Ligand binding to the TCR causes a conformational change at the CD3 subunits to expose the CD3ε cytoplasmic proline-rich sequence (PRS). It was suggested that the PRS is important for TCR signaling and T cell activation. It has been shown
Identification of the minimal tyrosine residues required for linker for activation of T cell function.
Lin, J and Weiss, A
The Journal of Biological Chemistry, 276, 29588-29595 (2001)
Joseph Lin et al.
The Journal of cell biology, 162(4), 673-682 (2003-08-13)
CD148 is a receptor-like protein tyrosine phosphatase up-regulated on T cells after T cell receptor (TCR) stimulation. To examine the physiologic role of CD148 in TCR signaling, we used an inducible CD148-expressing Jurkat T cell clone. Expression of CD148 inhibits
A Weiss et al.
The Journal of experimental medicine, 160(5), 1284-1299 (1984-11-01)
The association between T3 and the T cell antigen receptor was examined using the T3 bearing T cell leukemic line Jurkat. A monoclonal antibody, C305, was produced, which reacted with idiotypic-like determinants expressed on Jurkat. The molecule with which this
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