06-1433
抗phospho-FGFR-1 (Tyr653/Tyr654)抗体
from rabbit, purified by affinity chromatography
别名:
Basic fibroblast growth factor receptor 1, FGFR-1, bFGF-R-1, Fms-like tyrosine kinase 2, FLT-2, Proto-oncogene c-Fgr, CD331
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
human
Application:
cell based assay
western blot
western blot
Technique(s):
cell based assay: suitable
western blot: suitable
western blot: suitable
Citations:
15
Uniprot accession no.:
产品名称
抗phospho-FGFR-1 (Tyr653/Tyr654)抗体, from rabbit, purified by affinity chromatography
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
species reactivity (predicted by homology)
Xenopus (based on 100% sequence homology), mouse (based on 100% sequence homology), zebrafish (based on 100% sequence homology), chicken (based on 100% sequence homology), bovine (based on 100% sequence homology), rat (based on 100% sequence homology)
packaging
antibody small pack of 25 μg
technique(s)
cell based assay: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
ambient
target post-translational modification
phosphorylation (pTyr653/pTyr654)
Quality Level
Gene Information
human ... FGFR1(2260)
Preparation Note
自收到之日起，在 2-8°C 条下可稳定保存 1 年。
Analysis Note
对照
转染 FGFR-1 的未经处理和经 λ 磷酸酶处理的 HEK293T 细胞
转染 FGFR-1 的未经处理和经 λ 磷酸酶处理的 HEK293T 细胞
通过蛋白质印迹对转染了 FGFR1 的未经处理和经 λ 磷酸酶处理的 HEK293T 细胞进行了评估。
蛋白质印迹分析：0.2 µg/mL 的该抗体在 10 µg 转染了 FGFR1 的未经处理和经 λ 磷酸酶处理的 HEK293T 细胞中检测到 FGFR-1。
蛋白质印迹分析：0.2 µg/mL 的该抗体在 10 µg 转染了 FGFR1 的未经处理和经 λ 磷酸酶处理的 HEK293T 细胞中检测到 FGFR-1。
Application
使用经过验证可用于 WB 细胞功能分析的抗磷酸化 FGFR-1（Tyr653/Tyr654）抗体检测磷酸化 FGFR-1（Tyr653/Tyr654）。
研究子类别
细胞因子&细胞因子受体
细胞因子&细胞因子受体
研究类别
炎症&免疫学
炎症&免疫学
肽抑制分析：0.2 µg/mL 代表性批次抑制转染了 FGFR-1 的 HEK293T 细胞。
Biochem/physiol Actions
该抗体识别在 Tyr653/Tyr654 处磷酸化的 FGFR-1。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
FGFR-1（成纤维细胞生长因子受体 1）是蛋白质的基本成纤维细胞生长因子家族的成员，被认为在良性前列腺增生的诱导和传播中很重要。FGFR-1 的缺失会导致植入后死亡，并与神经乳链球蛋白和神经突生长有关。人们最近发现，在肾细胞癌患者中 FGFR-1 表达增加，并且 FGFR-1 也可能在早期肢体形成中起作用。
观测值〜145 kDa。
FGFR-1 具有 19 个同工型和 8 个潜在的糖基化位点，将未成熟形式的受体的预期大小增加至 120 kDa，将成熟形式的受体的预期大小增加至 145 kDa（Hisaoka, K., et al. (2011).JBC.286(24):21118-21128)。
FGFR-1 具有 19 个同工型和 8 个潜在的糖基化位点，将未成熟形式的受体的预期大小增加至 120 kDa，将成熟形式的受体的预期大小增加至 145 kDa（Hisaoka, K., et al. (2011).JBC.286(24):21118-21128)。
Immunogen
与 Tyr653/Tyr654 处磷酸化的人 FGFR-1 相对应的 KLH 偶联的线性肽。
表位：磷酸化 Tyr653/Tyr654
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Physical form
亲和纯化
在含 0.1 M Tris-甘氨酸（pH 7.4），150 mM NaCl 和 0.05％ 叠氮化钠的缓冲液中的纯化的兔多克隆抗体。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
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