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Merck
CN

06-203

Anti-SHC Antibody

Upstate®, from rabbit

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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biological source

rabbit

Quality Level

antibody product type

primary antibodies

clone

polyclonal

species reactivity

pig, rat, human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

Gene Information

human ... SHC1(6464)

General description

46, 52, 66 kDa

Immunogen

Recombinant GST fusion protein corresponding to amino acids 366-473 of human SHC-SH2

Application

Anti-SHC Antibody is an antibody against SHC for use in IH, IP & WB.
Research Category
Signaling
Research Sub Category
Cytoskeletal Signaling

Biochem/physiol Actions

Recognizes SHC proteins.

Physical form

Format: Purified
Immunoaffinity Purified immunoglobulin in 0.2 Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Protein A purified

Preparation Note

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Positive Control Included: Non-Stim A431 Cell Lysate (12-301)
routinely evaluated by immunoblot on RIPA lysates from human A431 carcinoma cells or mouse 3T3 RIPA cell lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

10-13 - German Storage Class 10 to 13

法规信息

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Fibroblast growth factor receptor (FGFR) and candidate signaling molecule distribution within rat and human retina.
Norbert Kinkl, Gregory S Hageman, Jose A Sahel, David Hicks
Molecular Vision null
Chemokine receptors CXCR-1/2 activate mitogen-activated protein kinase via the epidermal growth factor receptor in ovarian cancer cells.
G Venkatakrishnan, R Salgia, J E Groopman
The Journal of Biological Chemistry null
Kevin D Wright et al.
Breast cancer research : BCR, 21(1), 74-74 (2019-06-17)
SHC1 proteins (also called SHCA) exist in three functionally distinct isoforms (p46SHC, p52SHC, and p66SHC) that serve as intracellular adaptors for several key signaling pathways in breast cancer. Despite the broad evidence implicating SHC1 gene products as a central mediator