06-559
Anti-Pyk2 Antibody
Upstate®, from rabbit
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Species reactivity:
human, mouse
Application:
ICC, IP, WB
Citations:
34
biological source
rabbit
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
Gene Information
human ... PTK2B(2185)
species reactivity
human, mouse
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
General description
125 kDa
Immunogen
GST-fusion protein containing amino acids 726-863 of human Pyk2
Application
Research Category
Signaling
Signaling
Research Sub Category
Cytoskeletal Signaling
Cytoskeletal Signaling
This Anti-Pyk2 Antibody is validated for use in IC, IP, WB for the detection of Pyk2.
Biochem/physiol Actions
Recognizes Pyk2, and its degradation products; does not cross-react with FAK.
Physical form
Format: Purified
Protein A Purified immunoglobulin in 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
Protein A purified
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
Mouse brain cytosolic RIPA lysates
Mouse brain cytosolic RIPA lysates
routinely evaluated by immunoblot on mouse brain cytosolic RIPA lysates
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Rongfang Wei et al.
Cancer communications (London, England), 42(11), 1185-1206 (2022-08-31)
Multiple myeloma (MM) is the second most common hematological malignancy. An overwhelming majority of patients with MM progress to serious osteolytic bone disease. Aminoacyl-tRNA synthetase-interacting multifunctional protein 1 (AIMP1) participates in several steps during cancer development and osteoclast differentiation. This
Effects of the integrin-linked kinase inhibitor QLT0267 on squamous cell carcinoma of the head and neck.
Younes, MN; Yigitbasi, OG; Yazici, YD; Jasser, SA; Bucana, CD; El-Naggar, AK; Mills, GB; Myers, JN
Archives of Otolaryngology--Head & Neck Surgery null
S Eguchi et al.
Hypertension (Dallas, Tex. : 1979), 33(1 Pt 2), 201-206 (1999-02-04)
-PYK2, a recently identified Ca2+-sensitive tyrosine kinase, has been implicated in extracellular signal-regulated kinase (ERK) activation via several G protein-coupled receptors. We have reported that angiotensin II (Ang II) induces Ca2+-dependent transactivation of the epidermal growth factor receptor (EGFR) which
Shinichi Nakano et al.
Scientific reports, 9(1), 4236-4236 (2019-03-14)
Excessive osteoclastic bone erosion disrupts normal bone remodeling and leads to bone loss in many skeletal diseases, including inflammatory arthritis, such as rheumatoid arthritis (RA) and psoriatic arthritis, periodontitis and peri-prosthetic loosening. Functional control of osteoclasts is critical for the
Hydroxamic acid derivatives of mycophenolic acid inhibit histone deacetylase at the cellular level.
Daniela I Batovska,Dong Hoon Kim,Shinya Mitsuhashi,Yoon Sun Cho,Ho Jeong Kwon,Makoto Ubukata
Bioscience, Biotechnology, and Biochemistry null
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