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Merck
CN

07-001

Anti-p47-phox Antibody

serum, Upstate®

别名:

Anti-Anti-CGD1, Anti-Anti-NCF1A, Anti-Anti-NOXO2, Anti-Anti-SH3PXD1A, Anti-Anti-p47phox

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ICC, IP, WB
Citations:
18
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biological source

rabbit

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... NCF1(653361)

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General description

47 kDa

Immunogen

GST fusion protein corresponding to full-length human p47-phox

Application

Anti-p47-phox Antibody detects level of p47-phox & has been published & validated for use in IC, IP & WB.
Research Category
Neuroscience
Research Sub Category
Oxidative Stress

Biochem/physiol Actions

Recognizes p47 phox.

Physical form

Immunoaffinity Purified immunoglobulin in 0.2M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide, 5mg/ml BSA before the addition of glycerol to 30%
Unpurified

Preparation Note

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
HL-60 cell lysate
routinely evaluated by immunoblot on RIPA lysates from HL-60 cells

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

10 - Combustible liquids

wgk

WGK 1


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Molecular diagnosis of X-linked chronic granulomatous disease in Iran.
S Teimourian, Z Rezvani, M Badalzadeh, C Kannengiesser, D Mansouri, M Movahedi et al.
International Journal of Hematology null
Y Li et al.
Redox biology, 22, 101143-101143 (2019-03-22)
First described as essential to the phagocytic activity of leukocytes, Nox2-derived ROS have emerged as mediators of a range of cellular and tissue responses across species from salubrious to deleterious consequences. Knowledge of their role in inflammation is limited, however.
Eduardo Rebelato et al.
Life sciences, 91(7-8), 244-249 (2012-07-24)
NADPH oxidase (NOX) is a known source of superoxide anions in phagocytic and non-phagocytic cells. In this study, the presence of this enzyme in human pancreatic islets and the importance of NADPH oxidase in human β-cell function were investigated. In
Dena Parsa et al.
Molecular medicine (Cambridge, Mass.), 28(1), 60-60 (2022-06-07)
African Americans (AAs) are disproportionately affected by cardiovascular disease (CVD), they are 20% more likely to die from CVD than whites, chronic exposure to inflammation and oxidative stress contributes to CVD. In previous studies, enhancing parasympathetic cholinergic activity has been
Localization of a constitutively active, phagocyte-like NADPH oxidase in rabbit aortic adventitia: enhancement by angiotensin II
Pagano, P J, et al
Proceedings of the National Academy of Sciences of the USA, 94, 14483-14488 (1997)

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