07-1387
抗氧化-CaM激酶II（Met281/282）抗体
serum, from rabbit
别名:
CAMKK beta protein, CaM-KK beta, CaM-kinase kinase beta, CaMKK beta, Calcium/calmodulin-dependent protein kinase kinase beta, calcium/calmodulin-dependent protein kinase beta, calcium/calmodulin-dependent protein kinase kinase 2 beta, calcium/calmodulin-
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
serum
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
mouse, rat, human
技术
immunocytochemistry: suitable
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... CAMK2D(817)
一般描述
Ca2+/钙调蛋白依赖性激酶家族包括CaM激酶I至IV，磷酸化酶激酶和MLCK。在没有刺激的情况下，CaM激酶是无活性的。与Ca2+/钙调蛋白的结合诱导构象变化和激活。CaM激酶具有广泛的底物特异性，具有许多细胞功能。
60 kDa
免疫原
包含并包括氧化的Met281/282的合成肽。
表位：氧化Met281/282
应用
一个独立的实验室验证了该抗体在用盐水，AngII或Iso处理的小鼠心脏切片中的免疫细胞化学中起作用（Erickson，J.R.，2008）。
经验证，该抗氧化CaM激酶II（Met281/282）抗体可用于WB，IC检测氧化CaM激酶II（Met281/282）。
生化/生理作用
基于与免疫原序列的100%同源性，预期在小鼠和大鼠中发生交叉反应。
当在Met281/282上氧化时，该抗体可识别CaM激酶II。
制备说明
自收到之日起，在-20°C条件下可稳定保存1年。
处理建议：收到后，在取下瓶盖之前，将小瓶离心并轻轻混合溶液。
处理建议：收到后，在取下瓶盖之前，将小瓶离心并轻轻混合溶液。
分析说明
通过蛋白质印迹在未处理和经H2O2处理的小鼠心脏细胞裂解液中进行了评估。
蛋白质印迹分析： 该抗体的1:1,000稀释液用于检测小鼠心脏细胞裂解液中氧化的CaM激酶II。
蛋白质印迹分析： 该抗体的1:1,000稀释液用于检测小鼠心脏细胞裂解液中氧化的CaM激酶II。
其他说明
替代：04-1079
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
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