Anti-Rho GTPase-activating protein 23 Antibody

Rho GTPase-activating protein 23 is a multidomain cytoplasmic protein belonging to a large family of over 70 Rho-GAP proteins which regulate the activity of Rho GTPases. In general, Rho-GAP proteins enhance the activity of Rho GTPases resulting in more rapid inactivation of Rho GTPases. Rho-GAP proteins have been implicated in many cellular processes such as endocytosis, exocytosis, cytokinesis, cell migration, differentiation, and tumor suppression. Rho GTPase-activating protein 23, a relatively new member of this family, has been detected in prostate, placenta, hippocampus, medulla, and in various tumors, but its precise biological function is not yet clear.

~170 kDa observed. A doublet may be observed in certain lysates.

KLH-conjugated linear peptide corresponding to human Rho GTPase-activating protein 23.

Research Category
Signaling

Research Sub Category
Developmental Signaling

This Rho GTPase-activating protein 23 antibody is validated for use in WB for the detection of the Rho GTPase-activating protein 23 protein.

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Control
Mouse lung tissue lysate

Evaluated by Western Blot in mouse lung tissue lysate.

Western Blot Analysis: 0.1 µg/mL of this antibody detected Rho GTPase-activating protein 23 in 10 µg of mouse lung tissue lysate.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.