产品名称
抗乙酰组蛋白H4（Lys8）抗体, serum, Upstate®
biological source
rabbit
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, Saccharomyces cerevisiae
manufacturer/tradename
Upstate®
technique(s)
ChIP: suitable (ChIP-seq)
dot blot: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
acetylation (Lys8)
Quality Level
Gene Information
human ... H4C1(8359)
Analysis Note
对照
经丁酸钠处理的HeLa细胞
经丁酸钠处理的HeLa细胞
通过免疫印迹法对丁酸钠处理过的HeLa细胞的酸提取物进行了常规评估
Application
使用在ChIP、IP、WB、DB、ChIP-seq中验证的抗乙酰化组蛋白H4（Lys8）抗体（兔多克隆抗体）检测乙酰化组蛋白H4（Lys8），也称为H4K8Ac、组蛋白H4（乙酰基K8）。
General description
组蛋白H4是参与真核细胞染色质结构的5种主要组蛋白之一。H4具有一个主要的球状结构域和一个长N末端的尾巴，其与核糖体核小体′串珠′结构体的结构有关。
组蛋白H4的N末端尾部从球状核小体核心突起，其可能发生几种不同类型的表观遗传修饰，从而影响细胞过程。这些修饰包括甲基或乙酰基与赖氨酸和精氨酸的共价连接，以及丝氨酸或苏氨酸的磷酸化。
组蛋白H4的N末端尾部从球状核小体核心突起，其可能发生几种不同类型的表观遗传修饰，从而影响细胞过程。这些修饰包括甲基或乙酰基与赖氨酸和精氨酸的共价连接，以及丝氨酸或苏氨酸的磷酸化。
10 kDa
Immunogen
对应于其中赖氨酸8被乙酰化的酵母组蛋白H4（RGKGGAcKGLGKG-C）的氨基酸3-13的肽。
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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