07-377
抗核抗体
Upstate®, from rabbit
别名:
抗瓜氨酸化蛋白抗体
登录 查看组织和合同定价。
选择尺寸
关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
human, vertebrates, mouse
Application:
IHC, WB
Citations:
21
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human, vertebrates, mouse
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable, western blot: suitable
isotype
IgG
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
正在寻找类似产品? 访问 产品对比指南
General description
43-65 kDa
氨基酸瓜氨酸是肝脏从氨中解毒所必需的，氨是人体氧化的废物。瓜氨酸促进能量和帮助免疫系统。这种不寻常的氨基酸是在尿素循环中通过向鸟氨酸中加入二氧化碳和氨而形成的。接着与天冬氨酸结合形成精氨酸琥珀酸，然后被代谢成氨基酸精氨酸。
Immunogen
线状肽，含瓜氨酸。
Application
用抗瓜氨酸抗体（兔多克隆抗体）检测瓜氨酸，已证明可用于WB & IHC。
研究子类别
常规翻译后修改
常规翻译后修改
研究类别
炎症 & 免疫学
炎症 & 免疫学
Biochem/physiol Actions
人角质化皮肤中的多重脱位角蛋白。 在富含甘氨酸的环境中优先与瓜氨酸残基反应。
Physical form
25mM Tris/Tris-HCl，pH 7.4，137mM NaCl、2.7mM KCl、0.02%叠氮化钠，然后添加甘油至30％
免疫亲和纯化
Preparation Note
自收到之日起，在2-8°C条件下可稳定保存1年。
Analysis Note
对准
人外角化层全细胞裂解液
人外角化层全细胞裂解液
通过免疫印迹对带剥人角膜外层全细胞裂解液进行常规评估
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
WGK 1
Yi-Fang Yang et al.
Cellular & molecular biology letters, 27(1), 19-19 (2022-03-04)
Peptididylarginine deiminase type 2 (PADI2) catalyzes the conversion of arginine residues to citrulline residues on proteins. We demonstrate that PADI2 induces T cell activation and investigate how PADI2 promotes activated T cell autonomous death (ACAD). In activated Jurkat T cells
Hans-Georg Kopp et al.
The Journal of clinical investigation, 116(12), 3277-3291 (2006-12-05)
Thrombopoietic cells may differentially promote or inhibit tissue vascularization by releasing both pro- and antiangiogenic factors. However, the molecular determinants controlling the angiogenic phenotype of thrombopoietic cells remain unknown. Here, we show that expression and release of thrombospondins (TSPs) by
Maurizio Sorice et al.
Rheumatology (Oxford, England), 55(8), 1374-1385 (2016-04-15)
Autophagy may represent a functional processing event that creates a substrate for autoreactivity. In particular, autophagy may play a role in the pathogenesis of RA, since autophagy is a key cellular event involved in the generation of citrullinated peptides, with
T Senshu et al.
Biochemical and biophysical research communications, 225(3), 712-719 (1996-08-23)
The upper layers of mammalian epidermis contain citrulline-containing proteins formed by enzymatic deimination of arginine residues. To study the role of protein deimination in epidermal differentiation, we identified deiminated proteins extracted from human epidermis. Major deiminated proteins were identified as
T Senshu et al.
Journal of dermatological science, 21(2), 113-126 (1999-10-08)
Citrulline residues are detected in keratins and filaggrin in the cornified layers of mammalian epidermis. Such citrulline residues are formed by the enzymatic deimination of arginine residues by peptidylarginine deiminases (EC 3.5.3.15). Major deiminated keratins are derived from keratin K1.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持