生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
serum
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
human, rat, mouse, hamster
制造商/商品名称
Upstate®
技术
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
hamster ... Daxx(101836409)
human ... DAXX(1616)
mouse ... Daxx(13163)
rat ... Daxx(140926)
相关类别
一般描述
110 kDa
免疫原
GST fusion protein corresponding to residues 472-740 of human Daxx.
应用
Anti-Daxx Antibody is an antibody against Daxx for use in IP, WB & IC.
生化/生理作用
Daxx
分析说明
Control
Positive Antigen Control: Catalog #12-309, Hela cell nuclear extract. Add an equal volume of Laemmli reducing sample buffer to 10 μL of extract and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced extract per lane for minigels.
Positive Antigen Control: Catalog #12-309, Hela cell nuclear extract. Add an equal volume of Laemmli reducing sample buffer to 10 μL of extract and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced extract per lane for minigels.
routinely evaluated by immunoblot in HeLa nuclear extract
其他说明
Replaces: 04-445
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
An Adenovirus DNA Replication Factor, but Not Incoming Genome Complexes, Targets PML Nuclear Bodies.
Tetsuro Komatsu et al.
Journal of virology, 90(3), 1657-1667 (2015-11-27)
Promyelocytic leukemia protein nuclear bodies (PML-NBs) are subnuclear domains implicated in cellular antiviral responses. Despite the antiviral activity, several nuclear replicating DNA viruses use the domains as deposition sites for the incoming viral genomes and/or as sites for viral DNA
Adenovirus type 5 early region 1B 55K oncoprotein-dependent degradation of cellular factor Daxx is required for efficient transformation of primary rodent cells.
Schreiner, S; Wimmer, P; Groitl, P; Chen, SY; Blanchette, P; Branton, PE; Dobner, T
Journal of virology null
Roger D Everett
Journal of virology, 90(1), 167-179 (2015-10-16)
Intrinsic immunity is an aspect of antiviral defense that operates through diverse mechanisms at the intracellular level through a wide range of constitutively expressed cellular proteins. In the case of herpesviruses, intrinsic resistance involves the repression of viral gene expression
SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes.
Cuchet-Lourenco, D; Boutell, C; Lukashchuk, V; Grant, K; Sykes, A; Murray, J; Orr, A; Everett, RD
PLoS Pathogens null
Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes.
Schreiner, S; Burck, C; Glass, M; Groitl, P; Wimmer, P; Kinkley, S; Mund, A; Everett, RD; Dobner, T
Nucleic Acids Research null
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