biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, rat, mouse, hamster
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
hamster ... Daxx(101836409)
human ... DAXX(1616)
mouse ... Daxx(13163)
rat ... Daxx(140926)
General description
110 kDa
Immunogen
GST fusion protein corresponding to residues 472-740 of human Daxx.
Application
Anti-Daxx Antibody is an antibody against Daxx for use in IP, WB & IC.
Biochem/physiol Actions
Daxx
Analysis Note
Control
Positive Antigen Control: Catalog #12-309, Hela cell nuclear extract. Add an equal volume of Laemmli reducing sample buffer to 10 μL of extract and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced extract per lane for minigels.
Positive Antigen Control: Catalog #12-309, Hela cell nuclear extract. Add an equal volume of Laemmli reducing sample buffer to 10 μL of extract and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced extract per lane for minigels.
routinely evaluated by immunoblot in HeLa nuclear extract
Other Notes
Replaces: 04-445
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
PML isoforms I and II participate in PML-dependent restriction of HSV-1 replication.
Cuchet, D; Sykes, A; Nicolas, A; Orr, A; Murray, J; Sirma, H; Heeren, J; Bartelt, A; Everett, RD
Journal of Cell Science null
An Adenovirus DNA Replication Factor, but Not Incoming Genome Complexes, Targets PML Nuclear Bodies.
Tetsuro Komatsu et al.
Journal of virology, 90(3), 1657-1667 (2015-11-27)
Promyelocytic leukemia protein nuclear bodies (PML-NBs) are subnuclear domains implicated in cellular antiviral responses. Despite the antiviral activity, several nuclear replicating DNA viruses use the domains as deposition sites for the incoming viral genomes and/or as sites for viral DNA
Roger D Everett
Journal of virology, 90(1), 167-179 (2015-10-16)
Intrinsic immunity is an aspect of antiviral defense that operates through diverse mechanisms at the intracellular level through a wide range of constitutively expressed cellular proteins. In the case of herpesviruses, intrinsic resistance involves the repression of viral gene expression
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 07-471 | 04053252734441 |