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Merck
CN

07-471

Sigma-Aldrich

Anti-Daxx Antibody

serum, Upstate®

别名:

Anti-BING2, Anti-DAP6, Anti-EAP1, Anti-SMIM40

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关于此项目

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

serum

抗体产品类型

primary antibodies

克隆

polyclonal

种属反应性

human, rat, mouse, hamster

制造商/商品名称

Upstate®

技术

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同位素/亚型

IgG

NCBI登记号

UniProt登记号

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

hamster ... Daxx(101836409)
human ... DAXX(1616)
mouse ... Daxx(13163)
rat ... Daxx(140926)

相关类别

一般描述

110 kDa

免疫原

GST fusion protein corresponding to residues 472-740 of human Daxx.

应用

Anti-Daxx Antibody is an antibody against Daxx for use in IP, WB & IC.

生化/生理作用

Daxx

分析说明

Control
Positive Antigen Control: Catalog #12-309, Hela cell nuclear extract. Add an equal volume of Laemmli reducing sample buffer to 10 μL of extract and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced extract per lane for minigels.
routinely evaluated by immunoblot in HeLa nuclear extract

其他说明

Replaces: 04-445

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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储存分类代码

10 - Combustible liquids

WGK

WGK 2


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Tetsuro Komatsu et al.
Journal of virology, 90(3), 1657-1667 (2015-11-27)
Promyelocytic leukemia protein nuclear bodies (PML-NBs) are subnuclear domains implicated in cellular antiviral responses. Despite the antiviral activity, several nuclear replicating DNA viruses use the domains as deposition sites for the incoming viral genomes and/or as sites for viral DNA
Adenovirus type 5 early region 1B 55K oncoprotein-dependent degradation of cellular factor Daxx is required for efficient transformation of primary rodent cells.
Schreiner, S; Wimmer, P; Groitl, P; Chen, SY; Blanchette, P; Branton, PE; Dobner, T
Journal of virology null
Roger D Everett
Journal of virology, 90(1), 167-179 (2015-10-16)
Intrinsic immunity is an aspect of antiviral defense that operates through diverse mechanisms at the intracellular level through a wide range of constitutively expressed cellular proteins. In the case of herpesviruses, intrinsic resistance involves the repression of viral gene expression
SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes.
Cuchet-Lourenco, D; Boutell, C; Lukashchuk, V; Grant, K; Sykes, A; Murray, J; Orr, A; Everett, RD
PLoS Pathogens null
Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes.
Schreiner, S; Burck, C; Glass, M; Groitl, P; Wimmer, P; Kinkley, S; Mund, A; Everett, RD; Dobner, T
Nucleic Acids Research null

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