产品名称
抗乙酰基组蛋白H3（Lys36）抗体, serum, Upstate®
biological source
rabbit
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
multiplexing: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
acetylation (Lys36)
Quality Level
Gene Information
human ... H3F3B(3021)
Analysis Note
已通过免疫印迹进行常规评估。
Application
建议的稀释度：
蛋白质印迹：1：5000 - 1：20，000
ChIP分析：一个代表性批次被独立实验室用于进行IP（Gatta, R., et al. (2011）。Epigenetics.6(4):526-534.)
蛋白质印迹：1：5000 - 1：20，000
ChIP分析：一个代表性批次被独立实验室用于进行IP（Gatta, R., et al. (2011）。Epigenetics.6(4):526-534.)
使用在WB中验证过的抗乙酰基组蛋白H3（Lys36）抗体（兔多克隆抗体）检测乙酰基组蛋白H3（Lys36），也称H3K36Ac、组蛋白H3（乙酰基K36）。
研究子类别
组蛋白
组蛋白
研究类别
表观遗传学&核功能
表观遗传学&核功能
Biochem/physiol Actions
Lys36上乙酰化时识别组蛋白H3
预计具有广泛的物种交叉反应性
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
~17kDa
Immunogen
KLH偶联合成肽包含序列 ...GVAcK]KP...，其中 [AcK] 对应于人组蛋白H3的乙酰赖氨酸36。
Physical form
100μl 含有0.05％叠氮化钠和30％甘油的兔抗血清。
抗血清
Preparation Note
自运送之日起在-20°C下保存2年
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Anton Eberharter et al.
EMBO reports, 3(3), 224-229 (2002-03-08)
The organization of eukaryotic chromatin has a major impact on all nuclear processes involving DNA substrates. Gene expression is affected by the positioning of individual nucleosomes relative to regulatory sequence elements, by the folding of the nucleosomal fiber into higher-order
Cluster analysis reveals differential transcript profiles associated with resistance training-induced human skeletal muscle hypertrophy.
Thalacker-Mercer, A; Stec, M; Cui, X; Cross, J; Windham, S; Bamman, M
Physiological Genomics null
Endoplasmic reticulum stress-associated cone photoreceptor degeneration in cyclic nucleotide-gated channel deficiency.
Thapa, A; Morris, L; Xu, J; Ma, H; Michalakis, S; Biel, M; Ding, XQ
The Journal of Biological Chemistry null
Raffaella Gatta et al.
Epigenetics, 6(4), 526-534 (2011-02-10)
Histones post-translational modifications (PTMs) are crucial for transcriptional control, defining positive and negative chromatin territories. We previously described an extensive methylation-acetylation switch on cell cycle promoters using a single nucleosome ChIP assay. A key issue is how PTMs are locally
Jihye Jung et al.
Frontiers in microbiology, 11, 1978-1978 (2020-09-26)
Sound vibration (SV) is one of the several environmental stimuli that induce physiological changes in plants including changes in plant immunity. Immune activation is a complicated process involving epigenetic modifications, however, SV-induced epigenetic modifications remain unexplored. Here, we performed an
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