biological source
rabbit
Quality Level
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
Gene Information
human ... APOBEC3F(200316)
General description
51kDa An additional protein was also detected, Mr 31kDa
Immunogen
KLH-conjugated, synthetic peptide corresponding to amino acids 82-95 (C-DKVLKVLSPREEFK) of mouse apolipoprotein B editing complex 3 (Apobec3), with an N-terminal cysteine added for conjugation purposes.
Application
Anti-Apobec3 Antibody, NT is a high quality Rabbit Polyclonal Antibody for the detection of Apobec3 & has been validated in WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair
Cell Cycle, DNA Replication & Repair
Biochem/physiol Actions
Apobec3
Physical form
Affinity purified antibody in 0.1M Tris-Glycine, 0.15M NaCl, 0.05% Sodium Azide, pH 7.4.
ImmunoAffinity Purified
Preparation Note
Maintain for 1 year at 2 to 8°C from date of shipment.
Analysis Note
Routinely evaluated by immunoblot.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10-13 - German Storage Class 10 to 13
法规信息
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Ann M Sheehy et al.
Nature, 418(6898), 646-650 (2002-08-09)
Viruses have developed diverse non-immune strategies to counteract host-mediated mechanisms that confer resistance to infection. The Vif (virion infectivity factor) proteins are encoded by primate immunodeficiency viruses, most notably human immunodeficiency virus-1 (HIV-1). These proteins are potent regulators of virus
Adam Jarmuz et al.
Genomics, 79(3), 285-296 (2002-02-28)
The cytidine (C) to uridine (U) editing of apolipoprotein (apo) B mRNA is mediated by tissue-specific, RNA-binding cytidine deaminase APOBEC1. APOBEC1 is structurally homologous to Escherichia coli cytidine deaminase (ECCDA), but has evolved specific features required for RNA substrate binding
Yong-Hui Zheng et al.
Journal of virology, 78(11), 6073-6076 (2004-05-14)
Recently, APOBEC3G has been identified as a host factor that blocks retroviral replication. It introduces G to A hypermutations in newly synthesized minus strand viral cDNA at the step of reverse transcription in target cells. Here, we identified the human