09-230
Anti-phospho-Raptor (Thr706) Antibody
from rabbit, purified by affinity chromatography
别名:
P150 target of rapamycin (TOR)-scaffold protein, p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats, regulatory associated protein of mTOR
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
canine, human
Application:
DB, WB
Citations:
1
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
canine, human
species reactivity (predicted by homology)
horse (based on 100% sequence homology), mouse (based on 100% sequence homology), bovine (based on 100% sequence homology), dog (based on 100% sequence homology), rat (based on 100% sequence homology)
technique(s)
dot blot: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pThr706)
Gene Information
bovine ... Rptor(507056)
human ... RPTOR(57521)
General description
Raptor is a subunit of mTORC1 which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. Within mTORC1, Raptor positively regulates mTORC1 activity and functions as a scaffold for recruiting mTORC1 substrates.
~ 150 kDa
Immunogen
Epitope: Ser706
KLH-conjugated linear peptide corresponding to human Raptor phosphorylated at and around Thr706.
Application
Detect phospho-Raptor (Thr706) using this Anti-phospho-Raptor (Thr706) Antibody validated for use in WB, DB.
Biochem/physiol Actions
This antibody recognizes Raptor phosphorylated at Thr706.
Physical form
Purified rabbit serum in PBS with 0.05% sodium azide.
Analysis Note
Control
Modified and non modified peptides of phosphorylated and non-phosphorlyated Raptor protein
Modified and non modified peptides of phosphorylated and non-phosphorlyated Raptor protein
Evaluated by Dot Blot in modified and non modified peptides of phosphorylated and non-phosphorlyated Raptor protein.
Dot Blot Analysis: 1 µg/mL of this antibody detected Raptor in modified and non-modified peptides of phosphorylated and non-phosphorlyated Raptor protein.
Dot Blot Analysis: 1 µg/mL of this antibody detected Raptor in modified and non-modified peptides of phosphorylated and non-phosphorlyated Raptor protein.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Shijie Ma et al.
Oncogene, 41(17), 2431-2443 (2022-03-14)
eIF3a (eukaryotic translation initiation factor 3a), a subunit of the eIF3 complex, has been suggested to play a regulatory role in protein synthesis and in cellular response to DNA-damaging treatments. S6K1 is an effector and a mediator of mTOR complex
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