Quality Level
agency
ChP, NF, Ph. Eur.
product line
EMPROVE® EXPERT
form
solid
technique(s)
API processing | nano-milling: suitable
pH
5-7.5 (20 °C, 10 g/L in H2O)
mp
52 °C
transition temp
flash point 260 °C
density
1.06 g/cm3 at 25 °C
application(s)
liquid formulation
ophthalmics
parenterals
pharma/biopharma processes
pharmaceutical
semi-solid formulation
solid formulation
solubility enhancement
storage temp.
2-25°C
SMILES string
O2C(C2)C.O1CC1
InChI
1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
InChI key
RVGRUAULSDPKGF-UHFFFAOYSA-N
General description
Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
Application
Poloxamer 188 is used as surfactant in a variety of liquid formulations and acts e.g. as emulsifying, solubilizing and wetting agent.
Due to its low microbial and endotoxin limits, Poloxamer 188 Emprove® Expert is especially suitable for high-risk applications.
Due to its low microbial and endotoxin limits, Poloxamer 188 Emprove® Expert is especially suitable for high-risk applications.
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
Still not finding the right product?
Explore all of our products under 泊洛沙姆188
存储类别
11 - Combustible Solids
wgk
WGK 1
商品
This article outlines critical factors in long-term stability of proteins, and how different stabilizers protect again mechanical and thermal stress.
Instead of addressing API solubility during formulation, tackle it early during development. Read about the various methods for API processing.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 1371121000 | 04054839338489 |
| 1371120001 | 04054839338472 |
| 1371129025 | 04054839338502 |
| 1371129010 | 04054839338496 |