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Merck
CN

1.11714

3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide

for biochemistry

别名:

3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide, Thiazolyl blue, MTT

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关于此项目

经验公式(希尔记法):
C18H16BrN5S
化学文摘社编号:
分子量:
414.32
UNSPSC Code:
12352107
EC Index Number:
206-069-5
NACRES:
NA.21
MDL number:
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Quality Level

form

solid

mp

195 °C

solubility

10 g/L

storage temp.

2-30°C

SMILES string

[s]1c(nc(c1C)C)[n]2[n+](nc(n2)c4ccccc4)c3ccccc3.[Br-]

InChI

1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1

InChI key

AZKSAVLVSZKNRD-UHFFFAOYSA-M

Application

<ul>
<li><strong>Anal Biochem, 2017</strong>: Comparison of MTT and Neutral Red assays to assess cell viability in the presence of copper compounds, highlighting the versatility and sensitivity of the MTT assay in cytotoxicity testing (Gomez Perez et al., 2017).</li>
<li><strong>Indian J Pharmacol, 2016</strong>: Evaluation of the cytotoxic potential of various Indian fruit peels on liver cancer cells (HepG2) using MTT assay, providing insights into natural product research and potential anticancer properties (Garg et al., 2016).</li>
<li><strong>ACS Appl Mater Interfaces, 2015</strong>: Application in the real-time evaluation of live cancer cells, combining surface plasmon resonance and electrochemical methodologies with MTT assays for enhanced accuracy in viability testing (Wu et al., 2015).</li>
</ul>

Analysis Note

Assay (argentometric): ≥ 98
Identity (IR-spectrum): passes test
Spec. Absorptivity A 1%/1cm (242 nm; 0.001 %; 1 cm; methanol): 480 - 530
Heavy metals (as Pb): ≤ 0.001 %
Sulfated ash: ≤ 0.5 %


pictograms

Exclamation markHealth hazard

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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全球贸易项目编号

货号GTIN
111714001004022536135199
111714000104022536135182