Merck
CN

1.12635

SAFC

Parteck® Delta M(甘露醇)

EMPROVE® ESSENTIAL, Ph. Eur., BP, ChP, JP, USP, E 421

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别名:
D-甘露醇
经验公式(希尔记法):
C6H14O6
CAS号:
分子量:
182.17
MDL编号:
E编号:
E421
EC索引号:
200-711-8

Agency

BP
ChP
JP
Ph. Eur.
USP

质量水平

描述

EMPROVE® ESSENTIAL Ph Eur,BP,USP,JP,E 421

产品线

EMPROVE® ESSENTIAL

形式

fine powder

自燃温度

410 °C

效能

13500 mg/kg LD50, oral (Rat)

pH值(酸碱度)

5-7 (20 °C, 100 g/L in H2O)

bp

290-295 °C/4 hPa

mp

164-169 °C

应用

liquid formulation
pharmaceutical
solid formulation

储存温度

2-25°C

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2

InChI key

FBPFZTCFMRRESA-UHFFFAOYSA-N

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一般描述

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Parteck® Delta M excipient is a convertible mannitol specifically designed to handle wet granulation. Its delta-polymorphic crystals make it extremely adaptable. While it is monographed as a standard mannitol, this exceptional excipient changes its structure and converts into a beta-polymorph when it comes into contact with water. This creates a porous structure, thereby increasing the surface area, which leads to the ability to produce exceptionally hard tablets with fast disintegration.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 1


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