一般描述
A highly potent and selective antagonist of adenosine A2A receptor (Ki = 600 pM). Does not affect the activity of other adenosine receptors in any significant manner (Ki = 287 nM; 5.0 µM, and > 10 µM for A1, A2B, and A3 receptors, respectively). Displays neuroprotective effects in cerebral ischaemia in rats, and shown to counteract Parkinsonian-like muscle rigidity in rats.
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