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Merck
CN

1.20079

Millipore

ESHMUNO Q

Eshmuno® Q

别名:

Eshmuno® Q 树脂

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UNSPSC代码:
47101511

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质量水平

400

ligand

(Trimethylammoniumethyl)

无菌性

sterile (Caustic Stable)

产品线

Eshmuno®

表单

resin

特殊分析物

MAbs

参数

1000 cm/hr flow rate
1000 cm/hr max. flow rate
8 bar max. pressure

基质活性基团

polymer, polyvinyl ether

平均粒径

85 μm

容量

150 mg binding capacity (BSA/mg of resin)
 ~150 mg, BSA binding capacity

转变温度

flash point 35 °C (own results)

密度

1 g/cm3 at 20 °C

应用

recombinant protein
vaccine development

分离技术

anion exchange
mixed mode

储存温度

2-30°C

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一般描述

Eshmuno® Q resin is a strong anion exchange resin, coupling our renowned tentacle structure with a hydrophilic polyvinyl ether base matrix. Consequently, Eshmuno® Q resin offers outstanding results in typical anion exchange applications, such as removing biomolecules′ impurities in flow-through mode.

特点和优势

Eshmuno® Q chromatography resin enables:

  • Purification of acidic and neutral proteins and peptides from different sources, including plasma

Superior productivity for downstream processing of biomolecules
  • High flow rate versus pressure-flow behavior
  • Excellent removal of impurities, such as HCP, leached Protein A, and viruses
  • Robust and safe packing procedures
  • Strong chemical stability

包装

  • 1.20079.0100: Eshmuno® Q Resin 100ml
  • 1.20079.0010: Eshmuno® Q Resin 10ml
  • 1.20079.0500: Eshmuno® Q Resin 500ml
  • 1.20079.5000: Eshmuno® Q Resin 5L

Plastic bottle

分析说明

Appearance: Milky cream coloured turbid suspension, free from coarse mechanical impurities.
Microscopic evaluation: Spherical particles, no agglomerates, no fines.
Extractable matter (water): ≤ 0.08 %
Ionic capacity: 90 - 190 µeq/ml
Performance test (conalbumin): 9 - 19 mS/cm
Performance test (human serum albumin): 20 - 30 mS/cm
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Protein binding capacity(bovine serum albumin): 120 - 190 mg/ml
Particle size (50-120 µm): ≥ 80 %
Particle size (d50): 75 - 95 µm
Cerium: ≤ 30 µg/g
Endotoxins: ≤ 1.00 EU/ml
TAMC (total aerobic microbial count): ≤ 100 CFU/ml
TYMC (total yeast and mould count): ≤ 100 CFU/ml

法律信息

Eshmuno is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Flame
GHS02

警示用语：

Warning

危险声明

H226

危险分类

Flam. Liq. 3

储存分类代码

3 - Flammable liquids

WGK

WGK 1

闪点(°F)

95.0 °F

闪点(°C)

35 °C

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See case study examples of how to optimize chromatographic purification of plasmid DNA for Biopharmaceutical Applications.

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