1.37228
T7 RNA Polymerase
EMPROVE® EXPERT
可持续性特点
别名:
Polymerase, T7, T7 RNAP
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关于此项目
UNSPSC Code:
12352204
Specific activity:
≥50.000 units/mL
Assay:
≥95% (SDS-PAGE)
Biological source:
bacteriophage T7
Recombinant:
expressed in E. coli
biological source
bacteriophage T7
Quality Segment
recombinant
expressed in E. coli
grade
GMP, Halal, Kosher
product line
EMPROVE® EXPERT
assay
≥95% (SDS-PAGE)
form
aqueous solution
specific activity
≥50.000 units/mL
mol wt
99 kDa
sustainability
Sustainability features
technique(s)
in vitro transcription (IVT): suitable
suitability
suitable for (In‑vitro transcription (IVT))
application(s)
pharma/biopharma processes
pharmaceutical
foreign activity
Low endotoxin
Low bioburden
DNase: none detected
RNase: none detected
Nickase: none detected
storage temp.
-10 to -25°C
General description
mRNA technologies represent a revolutionary approach for prophylactic vaccines and for therapeutics, including cancer treatments and immunotherapies. As global interest in mRNA manufacturing grows and regulatory expectations become more stringent, manufacturers require raw materials suitable for pharmaceutical use with high quality and purity to enable successful mRNA production.
In response, we have developed the high-purity enzyme Emprove® Expert portfolio, compliant with IPEC-PQG GMP standards, to ensure batch-to-batch consistency in your mRNA manufacturing processes. These critical raw materials are accompanied by comprehensive Emprove® Dossiers, providing essential regulatory support to facilitate compliance and accelerate time to market in the biopharmaceutical industry.
As part of our SAFC® portfolio, these high-quality raw materials are designed to meet the specific needs of pharma and biopharma production.
In response, we have developed the high-purity enzyme Emprove® Expert portfolio, compliant with IPEC-PQG GMP standards, to ensure batch-to-batch consistency in your mRNA manufacturing processes. These critical raw materials are accompanied by comprehensive Emprove® Dossiers, providing essential regulatory support to facilitate compliance and accelerate time to market in the biopharmaceutical industry.
As part of our SAFC® portfolio, these high-quality raw materials are designed to meet the specific needs of pharma and biopharma production.
This productaligns with the Green Chemistry Principle of "Designing Safer Chemicals". It is a preparation with defined composition that replaces Triton X-100 with Tween-20, addressing concerns of Triton X-100 as an endocrine disruptor, delivering improved safety.
Application
T7 RNA polymerase is the core enzyme used in in vitro transcription (IVT) workflows for the production of messenger RNA (mRNA). It catalyzes the synthesis of RNA from a DNA template containing a T7 promoter sequence. Its high specificity and robust transcription efficiency make it the standard choice for manufacturing mRNA therapeutics and vaccines.
Features and Benefits
Our IVT enzyme Emprove® Expert IVT portfolio is designed to align with best-practice IVT methods for mRNA manufacturing and provides all purity requirements for reliable production of mRNA therapeutics and vaccines:
- High purity (≥95%)
- Low endotoxin and bioburden
- DNase and RNase-free
Packaging
137228.0001 / 1 mL / plastic vial
137228.0010 / 10 mL / plastic bottle
137228.0050 / 50 mL / plastic bottle
137228.0010 / 10 mL / plastic bottle
137228.0050 / 50 mL / plastic bottle
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
WGK
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable
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